• Home
  • Search Results
  • Evaluation of lipid peroxidation and antioxidant status on fenvalerate, nitrate and their co-exposure in Bubalus bubalis.

Evaluation of lipid peroxidation and antioxidant status on fenvalerate, nitrate and their co-exposure in Bubalus bubalis.

Pesticide biochemistry and physiology (2015-08-13)
Kamalpreet Kaur Gill, Harpal Singh Sandhu, Rajdeep Kaur
ABSTRACT

The toxic effects of pesticides and minerals have been explored in different species, but still there is paucity of information regarding their combined toxicological effects. The present investigation reports oxidative stress induced by oral subacute exposure to fenvalerate (1 mg/kg) and sodium nitrate (20 mg/kg) alone, as well as in combination daily for 21 days in buffalo calves. Fenvalerate exposure produced significant elevation in lipid peroxidation (LPO), glutathione peroxidase (GPx), while it produced significant decline in blood glutathione (GSH) levels, superoxide dismutase (SOD) and catalase (CAT). No significant alteration was evidenced in nitric oxide (NOx) levels. Oral exposure to sodium nitrate produced significant inclination in LPO and NOx, while on the other hand significant depreciation in SOD and CAT with no significant change in GPx activity. Combined exposure to fenvalerate and sodium nitrate produced severe effects with an appreciably more prominent elevation in extent of LPO and decline in blood GSH levels.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Sodium nitrate, ≥99.0%, suitable for plant cell culture
Sigma-Aldrich
Sodium nitrate, BioXtra, ≥99.0%
Sigma-Aldrich
Sodium nitrate, 99.995% trace metals basis
Sigma-Aldrich
Sodium nitrate, BioUltra, ≥99.0% (T)
Sigma-Aldrich
Sodium nitrate-14N, 99.95 atom % 14N