Polytriazoles as copper(I)-stabilizing ligands in catalysis.

Organic letters (2004-08-28)
Timothy R Chan, Robert Hilgraf, K Barry Sharpless, Valery V Fokin
ABSTRACT

Polytriazolylamines were synthesized by the copper(I)-catalyzed ligation of azides and alkynes. The C3-symmetric derivative, TBTA, was shown to be a powerful stabilizing ligand for copper(I), protecting it from oxidation and disproportionation, while enhancing its catalytic activity.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Tris(3-hydroxypropyltriazolylmethyl)amine, 95%
Sigma-Aldrich
Tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine, 97%