685143

Sigma-Aldrich

PEPPSI-IPr, ChemDose tablets

Loading: 2μmol per tablet

Synonym(s):
ChemDose, [1,3-Bis(2,6-diisopropylphenyl)imidazol-2-ylidene] (3-chloropyridyl)palladium(II) dichloride impregnated tablets, PEPPSI-IPr impregnated tablets
Empirical Formula (Hill Notation):
C32H40Cl3N3Pd
Molecular Weight:
679.46
MDL number:
PubChem Substance ID:

matrix

Magnesium aluminometasilicate base material

InChI

1S/C27H38N2.C5H4ClN.2ClH.Pd/c1-18(2)22-11-9-12-23(19(3)4)26(22)28-15-16-29(17-28)27-24(20(5)6)13-10-14-25(27)21(7)8;6-5-2-1-3-7-4-5;;;/h9-16,18-21H,17H2,1-8H3;1-4H;2*1H;/q;;;;+2/p-2

InChI key

BLDKGTGQENJFON-UHFFFAOYSA-L

Legal Information

ChemDose is a trademark of Reaxa Ltd.
PEPPSI is a trademark of Total Synthesis Ltd.

Pictograms

Health hazard

Signal Word

Warning

Hazard Statements

Precautionary Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

3

Certificate of Analysis
Certificate of Origin
  1. Which document(s) contains shelf-life or expiration date information for a given product?

    If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.

  2. How do I get lot-specific information or a Certificate of Analysis?

    The lot specific COA document can be found by entering the lot number above under the "Documents" section.

  3. What are the ChemDose® tablets made from? How big are the tablets?

    The tablets themselves are composed of a chemically inert magnesium aluminosilicate matrix, along with the adsorbed reagent or catalyst. All tablets are approximately 5 millimeters in diameter. The tablets for 685593 are approximately 10 millimeters in diameter.  For additional information on ChemDose products please visit the ChemDose Information site. 

  4. Where do I find information on the exact loading for a given lot of a ChemDose® product?

    The certificate of analysis (C of A) contains lot specific loading information, along with the method used for the loading determination. For additional information on ChemDose products please visit the ChemDose Information site. 

  5. How should I dispose of spent ChemDose® tablets?

    They should be treated as solid waste, contaminated with reaction species. The matrix is non-toxic and environmentally benign. For additional information on ChemDose products please visit the ChemDose Information site. 

  6. How should I store ChemDose® tablets?

    As with most catalysts and ligands, as a general precaution it is best to store them in a refrigerator and/or under an inert atmosphere to maintain activity. Some catalysts, such as Pd(dppf)Cl2·CH2Cl2, are more robust and can be handled in air without issue. Please refer to the ChemDose® label for specific handling of a given catalyst, ligand, or reagent. For additional information on ChemDose products please visit the ChemDose Information site. 

  7. Can I use ChemDose® tablets in any solvent?

    Yes, including aqueous solvents. For additional information on ChemDose products please visit the ChemDose Information site. 

  8. Do the ChemDose® tablets disintegrate during the course of the reaction?

    They are normally recovered intact, however, they may disintegrate somewhat in aqueous reactions. Any disintegrated tablets can be removed from the reaction via filtration. For additional information on ChemDose products please visit the ChemDose Information site. 

  9. What is the pH stability of the ChemDose® tablets?

    The ChemDose® tablets are mildly basic and will dissolve in the presence of mineral acids.  For additional information on ChemDose products please visit the ChemDose Information site. 

  10. Can I use ChemDose® tablets in a microwave or pressure vessel?

    Absolutely. Please see the Technical Information for Download section (below) for additional examples of cross-coupling reactions involving the use of microwaves.  For additional information on ChemDose products please visit the ChemDose Information site. 

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