724815

Sigma-Aldrich

Poly(N-isopropylacrylamide), carboxylic acid terminated

average Mn 2,000

Synonym(s):
PNIPAM-COOH, functionalized polyNIPAM, functionalized polyacrylamide, Polyacrylamide, NIPAM polymer, polyNIPAM
Linear Formula:
(C6H11NO)nSCH2CH2CO2H
NACRES:
NA.23

form

powder

Quality Level

mol wt

average Mn 2,000

mp

>300 °C

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Application

Novel polymer for development of thermosensitive coated micro/nano materials including thermoresponsive polymeric drug delivery systems. The carboxylic acid functional group can be used to conjugate a variety of biomolecules to the polymer chain.

Packaging

1, 5 g in glass bottle

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
Articles
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Wide range of functional polymers for biomedical applications have been synthesized and structurally characterized. Several classes of polymers including biodegradable polymers, hydrophilic & amphiphilic polymers, and stimuli responsive polymers have been prepared using controlled and directed functionalization via "living" polymerization such as RAFT, ionic and ring opening polymerization. Selected polymers have been studied for their structure-properties relationship. "
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Biomaterials science involves the design and fabrication of smart materials for studying, directing, or mimicking biology. For successful integration of biomaterials in biological research, a meaningful understanding of biological systems is required.
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Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.
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