Samarium(II)-iodide-mediated cyclizations in natural product synthesis.
David J Edmonds et al.
Chemical reviews, 104(7), 3371-3404 (2004-07-15)
Michal Szostak et al.
Chemical communications (Cambridge, England), 48(3), 330-346 (2011-09-01)
Samarium diiodide (SmI(2)) is one of the most important reductive electron transfer reagents available in the laboratory. Key to the popularity of SmI(2) is the ability of additives and co-solvents to tune the properties of the reagent. Over the last...
Pete Anderson et al.
Expert review of anticancer therapy, 7(11), 1517-1527 (2007-11-21)
Radiation therapy can be an effective means to treat bone metastases, which occur in more than 50% of cancer patients. (153)Samarium lexidronam ((153)Sm-EDTMP; Quadramet, Cytogen) is a radiopharmaceutical designed for deposition into bone metastases. Bone scans can identify patients that...
Expert opinion on pharmacotherapy, 7(11), 1475-1486 (2006-07-25)
Samarium-153 lexidronam (153Sm-EDTMP) is FDA approved for painful osteoblastic bone metastases that image on bone scan. 153Sm-EDTMP decay has a therapeutic beta-emission and a gamma-photon for bone scan imaging. Monitoring of osteosarcoma radiation treatment effectiveness was performed with bone, CT...
Jose M Concellón et al.
Chemical Society reviews, 33(9), 599-609 (2004-12-14)
The development of methodologies for the formation of carbon-carbon double bonds could be considered one of the most important challenges in organic synthesis. To this end, beta-elimination reactions in 1,2-difunctionalised substrates have been one of the most important means of...