A1968

Sigma-Aldrich

Ascorbic acid 6-palmitate

meets USP testing specifications

Synonym(s):
L-Ascorbic acid 6-hexadecanoate, NSC 402451, Ascorbic acid 6-palmitate, L-Ascorbyl palmitate, 6-O-Palmitoyl-L-ascorbic acid
Empirical Formula (Hill Notation):
C22H38O7
CAS Number:
Molecular Weight:
414.53
Beilstein/REAXYS Number:
96552
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.21

Quality Level

biological source

synthetic

Agency/Method

USP/NF
meets USP testing specifications

assay

95.0-100.5%

form

powder

color

light yellow

Featured Industry

Pharmaceutical (small molecule)

SMILES string

CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O

InChI

1S/C22H38O7/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(24)28-16-17(23)21-19(25)20(26)22(27)29-21/h17,21,23,25-26H,2-16H2,1H3/t17-,21+/m0/s1

InChI key

QAQJMLQRFWZOBN-LAUBAEHRSA-N

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General description

Ascorbic acid 6-palmitate/L-Ascorbyl 6-palmitate (AP) is a derivative of a synthetic lipophilic ascorbic acid.

Packaging

1 kg in poly drum
25, 100 g in poly bottle

Biochem/physiol Actions

L-Ascorbyl 6-palmitate (AP) is used as preservative in foods. In mice, AP works as a dietary antitumor promoter. 

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis
Certificate of Origin
A comparison of L-ascorbic acid and L-ascorbyl 6-palmitate utilization in Guinea Pigs and humans
Johnston CS, et al.
Nutrition Research (New York, N.Y.), 14(10), 1465-1471 (1994)
P O Nnamani et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 76(1), 68-74 (2010-06-18)
P90Gylation refers to the modification of lipid molecules by one or more phospholipid chains. Phospholipon 90G (P90G) contains about 94.0% of phosphatidylcholine stabilized with 0.1% ascorbyl palmitate and is a safe (GRAS) FDA-approved parenteral excipient with wide applications in drug...
L Capretto et al.
International journal of pharmaceutics, 440(2), 195-206 (2012-08-14)
The current paper reports the production of polymeric micelles (PMs), based on pluronic block-copolymers, as drug carriers, precisely controlling the cellular delivery of drugs with various physico-chemical characteristics. PMs were produced with a microfluidic platform to exploit further control on...
Bente M Jensen et al.
Journal of agricultural and food chemistry, 59(24), 13012-13017 (2011-11-11)
Whey fat has a relatively high level of unsaturated fatty acids, and as such, whey products with a high fat content are vulnerable to oxidation. The purposes of the present study were to assess the oxidative development in whey fat...
Rangrong Yoksan et al.
Colloids and surfaces. B, Biointerfaces, 76(1), 292-297 (2009-12-17)
The encapsulation of ascorbyl palmitate (AP) in chitosan particles was carried out by droplet formation via an oil-in-water emulsion, followed by droplet solidification via ionic gelation using sodium triphosphate pentabasic (TPP) as a cross-linking agent. The success of AP encapsulation...

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