D5899

Sigma-Aldrich

2-Deoxy-D-ribose

BioReagent, suitable for cell culture

Synonym(s):
2-Deoxy-D-arabinose, 2-Deoxy-D-erythropentose, Thyminose
Empirical Formula (Hill Notation):
C5H10O4
CAS Number:
Molecular Weight:
134.13
Beilstein/REAXYS Number:
1721978
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.75

Quality Level

biological source

synthetic (organic)

product line

BioReagent

assay

≥99% (GC)

form

powder

application(s)

cell culture | mammalian: suitable

mp

89-90 °C (lit.)

solubility

water: 100 mg/mL, clear to slightly hazy, colorless to light yellow

storage temp.

2-8°C

SMILES string

OC[C@@H](O)[C@@H](O)CC=O

InChI

1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m0/s1

InChI key

ASJSAQIRZKANQN-CRCLSJGQSA-N

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Flash Point(F)

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Flash Point(C)

Not applicable

Manuel Ellermann et al.
Acta crystallographica. Section D, Biological crystallography, 68(Pt 3), 253-260 (2012-02-22)
The biological activity of catechol neurotransmitters such as dopamine in the synapse is modulated by transporters and enzymes. Catechol-O-methyltransferase (COMT; EC 2.1.1.6) inactivates neurotransmitters by catalyzing the transfer of a methyl group from S-adenosylmethionine to catechols in the presence of...
Tymofii Yu Nikolaienko et al.
Physical chemistry chemical physics : PCCP, 14(44), 15554-15561 (2012-10-18)
Relaxed force constants (RFC) and vibrational root-mean-square (VRMS) deviations are used for comparative characterization of mechanical properties of canonical 2'-deoxyribonucleosides (2DRs) and 1,2-dideoxyribose molecule, their model sugar residue. It has been shown that RFC and VRMS should be preferred over...
Buthina Al-Oudat et al.
Bioorganic & medicinal chemistry letters, 23(3), 854-859 (2012-12-26)
Well-defined substrates for the study of oxidative processes are important for the elucidation of the role of DNA damage in the etiology of diseases such as cancer. We have synthesized 3'-modified oligodeoxyribonucleotides (ODNs) using 5'→3' 'reverse' DNA synthesis for the...
Waseem Hassan et al.
Chemico-biological interactions, 199(2), 96-105 (2012-06-12)
The study was designed to explore the biochemical influence of non bonding nitrogen interactions (N⋯Se/S) on organochalcogens potency. Approximately five and six times higher thiol peroxidase (TPx) like activity was observed for compound (C)-2 than C-1 and C-3, respectively. C-2...
Anita R Peoples et al.
Nucleic acids research, 40(13), 6060-6069 (2012-04-03)
Our mechanistic understanding of damage formation in DNA by the direct effect relies heavily on what is known of free radical intermediates studied by EPR spectroscopy. Bridging this information to stable product formation requires methods with comparable sensitivities, a criterion...

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