P6354

Sigma-Aldrich

1,2-Dioleoyl-sn-glycero-3-phosphocholine

lyophilized powder

Synonym(s):
3-sn-Phosphatidylcholine, 1,2-dioleoyl, PC, L-α-Phosphatidylcholine, dioleoyl, 1,2-Di(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine, L-β,γ-Dioleoyl-α-lecithin, DOPC
Empirical Formula (Hill Notation):
C44H84NO8P
CAS Number:
Molecular Weight:
786.11
Beilstein/REAXYS Number:
3898070
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.25

Quality Level

biological source

synthetic (organic)

assay

≥99% (TLC)

form

lyophilized powder

functional group

phospholipid

shipped in

ambient

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,42H,6-19,24-41H2,1-5H3/b22-20-,23-21-/t42-/m1/s1

InChI key

SNKAWJBJQDLSFF-NVKMUCNASA-N

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Application

1,2-Dioleoyl-sn-glycero-3-phosphocholine has been used for the reconstitution of proteoliposome (PL). It has also been used in the preparation of lipid vesicles.

Packaging

Packaged under Argon

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

RIDADR

NONH for all modes of transport

WGK Germany

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificate of Analysis

Certificate of Origin

Camila Fabiano de Freitas et al.
Colloids and surfaces. B, Biointerfaces, 181, 837-844 (2019-06-30)
Liposomes are membrane models and excellent Drug Delivery Systems. However, their preparation is expensive, labor intensive, time consuming, and sometimes toxic. Recently, we published an innovative methodology for the production of homogeneous Small Unilamellar Vesicles (SUV) through a simple, fast...
Lu Huang et al.
PLoS biology, 15(8), e2001750-e2001750 (2017-08-19)
As the central hub of the metabolism machinery, the mammalian target of rapamycin complex 2 (mTORC2) has been well studied in lymphocytes. As an obligatory component of mTORC2, the role of Rictor in T cells is well established. However, the...
Arman Fathizadeh et al.
The journal of physical chemistry. B, 123(31), 6792-6798 (2019-07-16)
We investigate membrane permeation by the peptide WKW that is amidated at its C-terminus and therefore carries a positive charge of +2. To facilitate an efficient calculation, we introduce a novel set of simple coarse variables that measure permeation depth...
Hydrodynamic lift of vesicles under shear flow in microgravity
Callens N, et al.
EPL, 83(2), 24002-24002 (2008)
Jessica J Hung et al.
Soft matter, 15(33), 6660-6676 (2019-08-08)
The dynamic behavior of monoclonal antibodies (mAbs) at high concentration provides insight into protein microstructure and protein-protein interactions (PPI) that influence solution viscosity and protein stability. At high concentration, interpretation of the collective-diffusion coefficient Dc, as determined by dynamic light...
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