Diethylene glycol

United States Pharmacopeia (USP) Reference Standard

2,2′-Oxydiethanol, 2-Hydroxyethyl ether, Diglycol, Bis(2-hydroxyethyl) ether
Linear Formula:
CAS Number:
Molecular Weight:
Beilstein/REAXYS Number:
MDL number:
PubChem Substance ID:

vapor density

2.14 (vs air)

vapor pressure

0.01 mmHg ( 20 °C)



autoignition temp.

442 °F

expl. lim.

2-12.3 %



refractive index

n20/D 1.447 (lit.)


245 °C (lit.)


−10 °C (lit.)


1.118 g/mL at 25 °C (lit.)

Featured Industry

Pharmaceutical (small molecule)



SMILES string




InChI key


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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.
Sales restrictions may apply.


Exclamation mark

Signal Word


Hazard Statements

Precautionary Statements


NONH for all modes of transport

WGK Germany


Flash Point(F)

280.4 °F - closed cup

Flash Point(C)

138 °C - closed cup

Joshua G Schier et al.
Journal of public health policy, 30(2), 127-143 (2009-07-15)
Diethylene glycol (DEG), an extremely toxic chemical, has been implicated as the etiologic agent in at least 12 medication-associated mass poisonings over the last 70 years. Why DEG mass poisonings occur remains unclear. Most reports do not contain detailed reports...
Leo J Schep et al.
Clinical toxicology (Philadelphia, Pa.), 47(6), 525-535 (2009-07-10)
Diethylene glycol (DEG) is a clear, colorless, practically odorless, viscous, hygroscopic liquid with a sweetish taste. In addition to its use in a wide range of industrial products, it has also been involved in a number of prominent mass poisonings...
Nestor R Sosa et al.
Annals of emergency medicine, 64(1), 38-47 (2014-01-21)
Diethylene glycol is a toxic industrial solvent responsible for more than 13 mass poisonings since 1937. Little is known about the clinical spectrum, progression, and neurotoxic potential of diethylene glycol-associated disease because of its high mortality and the absence of...
J L Hébert et al.
La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 59(5), 344-349 (1983-02-03)
Although acute poisoning with ethylene glycol (EG) used in antifreeze mixtures is well known in man, only a few reports have described acute intoxication with diethylene glycol (DEG) and only one has mentioned oxaluria. Furthermore, there is no experimental evidence...
Yunyan Gu et al.
Oncotarget, 6(4), 2397-2406 (2014-12-30)
Ovarian cancer patients carrying alterations (i.e., germline mutations, somatic mutations, hypermethylations and/or deletions) of BRCA1 or BRCA2 (BRCA1/2) have a better prognosis than BRCA1/2 alteration non-carriers. However, patients with wild-type BRCA1/2 may also have a favorable prognosis as a result...
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