Showing 1-30 of 386 results for "M3671"
Bastian Daniel et al.
The Journal of biological chemistry, 290(30), 18770-18781 (2015-06-04)
Plant genomes contain a large number of genes encoding for berberine bridge enzyme (BBE)-like enzymes. Despite the widespread occurrence and abundance of this protein family in the plant kingdom, the biochemical function remains largely unexplored. In this study, we have...
K Anu et al.
Indian journal of experimental biology, 53(6), 329-334 (2015-07-15)
Piper colubrinum Link., a distant relative of Piper nigrum L., is immune to the oomycete pathogen Phytophthora capsici Leonian that causes 'quick wilt' in cultivated black pepper (P. nigrum). The osmotin, PR5 gene homologue, earlier identified from P. colubrinum, showed...
Kathryn Bartley et al.
International journal for parasitology, 45(13), 819-830 (2015-08-25)
An aqueous extract of the haematophagous poultry ectoparasite, Dermanyssus gallinae, was subfractionated using anion exchange chromatography. Six of these subfractions were used to immunise hens and the blood from these hens was fed, in vitro, to poultry red mites. Mite...
Aitor Sánchez-Ferrero et al.
Biomaterials, 68, 42-53 (2015-08-13)
Bone tissue engineering demands alternatives overcoming the limitations of traditional approaches in the context of a constantly aging global population. In the present study, elastin-like recombinamers hydrogels were produced by means of carbodiimide-catalyzed crosslinking with citric acid, a molecule suggested...
Yue Yuan et al.
Biochemistry, 50(34), 7350-7360 (2011-08-03)
This study is aimed at investigating the molecular basis of environmental adaptation of woolly mammoth hemoglobin (Hb) to the harsh thermal conditions of the Pleistocene ice ages. To this end, we have carried out a comparative biochemical-biophysical characterization of the...
Karl J Erlandson et al.
Journal of virology, 88(19), 11576-11585 (2014-08-01)
Specific gene duplications can enable double-stranded DNA viruses to adapt rapidly to environmental pressures despite the low mutation rate of their high-fidelity DNA polymerases. We report on the rapid positive selection of a novel vaccinia virus genomic duplication mutant in...
Portable microfluidic integrated plasmonic platform for pathogen detection
Tokel, Onur, et al.
Scientific Reports, 2015, 9152-9152 null
Impaired lipoprotein receptor-mediated peripheral binding of plasma amyloid-? is an early biomarker for mild cognitive impairment preceding Alzheimer's disease.
Sagare, Abhay P., et al.
Journal of Alzheimer'S Disease, 24 (1), 25-34 (2011)
Takanori Moriyama et al.
PloS one, 10(5), e0119169-e0119169 (2015-05-29)
Soluble royal jelly protein is a candidate factor responsible for mammiferous cell proliferation. Major royal jelly protein 1 (MRJP1), which consists of oligomeric and monomeric forms, is an abundant proliferative protein in royal jelly. We previously reported that MRJP1 oligomer...
Hiroaki Ueda et al.
Plant physiology, 169(1), 138-147 (2015-05-17)
Leaf senescence is not a passive degenerative process; it represents a process of nutrient relocation, in which materials are salvaged for growth at a later stage or to produce the next generation. Leaf senescence is regulated by various factors, such...
Dyana Sanchez et al.
The FEBS journal, 282(8), 1538-1553 (2015-02-24)
The ComD-ComE two-component system controls the competence state of Streptococcus pneumoniae via the phospho-regulation of ComE, which fluctuates between monomeric and dimeric states. We previously showed that the non-phosphorylatable ComE(D) (58A) mutant is monomeric in solution, whereas the ComE(D) (58E) active...
Yoshihiro Ojima et al.
Applied and environmental microbiology, 81(17), 5900-5906 (2015-06-21)
Microbial flocculation is a phenomenon of aggregation of dispersed bacterial cells in the form of flocs or flakes. In this study, the mechanism of spontaneous flocculation of Escherichia coli cells by overexpression of the bcsB gene was investigated. The flocculation...
Tushar Dubey et al.
Scientific reports, 10(1), 12380-12380 (2020-07-25)
The intracellular Tau aggregates are known to be associated with Alzheimer's disease. The inhibition of Tau aggregation is an important strategy for screening of therapeutic molecules in Alzheimer's disease. Several classes of dyes possess a unique property of photo-excitation, which...
Andreas Herchenhan et al.
The Journal of biological chemistry, 290(26), 16440-16450 (2015-05-17)
Lysyl oxidases (LOXs) are a family of copper-dependent oxido-deaminases that can modify the side chain of lysyl residues in collagen and elastin, thereby leading to the spontaneous formation of non-reducible aldehyde-derived interpolypeptide chain cross-links. The consequences of LOX inhibition in...
Baoguang Li et al.
Applied and environmental microbiology, 81(24), 8243-8253 (2015-09-20)
Our previous work indicated a predominance (56.8%) of Salmonella enterica serovar Newport among isolates recovered from irrigation ponds used in produce farms over a 2-year period (B. Li et al., Appl Environ Microbiol 80:6355-6365, http://dx.doi.org/10.1128/AEM.02063-14). This observation provided a valuable...
K Nakajo et al.
Caries research, 44(5), 431-437 (2010-09-04)
Oral Bifidobacteriaceae, Bifidobacterium dentium and Bifidobacterium longum, are known to be isolated together with mutans streptococci and lactobacilli from caries lesions, suggesting that these Bifidobacteriaceae are caries associated and acid resistant. This study aimed to investigate effects of acidification on...
Mie Kristensen et al.
The AAPS journal, 17(5), 1200-1209 (2015-05-21)
Penetratin is a widely used carrier peptide showing promising potential for mucosal delivery of therapeutic proteins. In the present study, the importance of specific penetratin residues and pH was investigated with respect to complexation with insulin and subsequent transepithelial insulin...
Michiko Nakamura et al.
Progress in neuro-psychopharmacology & biological psychiatry, 64, 35-43 (2015-07-16)
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for the treatment of inflammatory pain. It is well established that NSAIDs exert their analgesic effects by inhibiting cyclooxygenase to prevent the production of prostaglandins; however, several NSAIDs including diclofenac also modulate other...
Harin Jung et al.
Plant science : an international journal of experimental plant biology, 236, 304-312 (2015-05-31)
Auxin signaling is a fundamental part of many plant growth processes and stress responses and operates through Aux/IAA protein degradation and the transmission of the signal via auxin response factors (ARFs). A total of 31 Aux/IAA genes have been identified...
Maria Amvrosiadou et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1006, 201-208 (2015-11-19)
Wilson's disease is an inherited disorder of copper transport in the hepatocytes with a wide range of genotype and phenotype characteristics. Mutations in the ATP7B gene are responsible for the disease. Approximately, over 500 mutations in the ATP7B gene have...
Alyssa K Van Dreumel et al.
Journal of clinical microbiology, 53(6), 1797-1805 (2015-03-20)
An amino acid consensus sequence for the seven serotypes of foot-and-mouth disease virus (FMDV) nonstructural protein 3B, including all three contiguous repeats, and its use in the development of a pan-serotype diagnostic test for all seven FMDV serotypes are described....
Tsuyoshi Shirai et al.
Journal of molecular biology, 321(5), 879-889 (2002-09-11)
The crystal structure of congerin II, a galectin family lectin from conger eel, was determined at 1.45A resolution. The previously determined structure of its isoform, congerin I, had revealed a fold evolution via strand swap; however, the structure of congerin...
Pankaj Kumar et al.
Veterinary research, 46, 79-79 (2015-07-15)
Turkey adenovirus 3 (TAdV-3) causes high mortality and significant economic losses to the turkey industry. However, little is known about the molecular determinants required for viral replication and pathogenesis. Moreover, TAdV-3 does not grow well in cell culture, thus detailed...
Jean-Philippe Semblat et al.
Molecular and biochemical parasitology, 201(1), 76-82 (2015-06-23)
Binding of host immunoglobulin is a common immune evasion mechanism demonstrated by microbial pathogens. Previous work showed that the malaria parasite Plasmodium falciparum binds the Fc-region of human IgM molecules, resulting in a coating of IgM on the surface of...
Chenyi Mao et al.
Science advances, 6(22), eaba4542-eaba4542 (2020-06-11)
Fluorescence microscopy is a workhorse tool in biomedical imaging but often poses substantial challenges to practitioners in achieving bright or uniform labeling. In addition, while antibodies are effective specific labels, their reproducibility is often inconsistent, and they are difficult to...
Valeria Valsecchi et al.
PloS one, 10(6), e0128560-e0128560 (2015-06-02)
Spinal muscular atrophy (SMA) is a severe neuromuscular disease, the most common in infancy, and the third one among young people under 18 years. The major pathological landmark of SMA is a selective degeneration of lower motor neurons, resulting in...
Lingyao Kong et al.
Nature communications, 6, 8630-8630 (2015-10-21)
Clade A protein phosphatase 2Cs (PP2Cs) are abscisic acid (ABA) co-receptors that block ABA signalling by inhibiting the downstream protein kinases. ABA signalling is activated after PP2Cs are inhibited by ABA-bound PYR/PYL/RCAR ABA receptors (PYLs) in Arabidopsis. However, whether these...
N Singh et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 968, 105-111 (2014-04-08)
SIRT6 is a histone deacetylase that has been proposed as a potential therapeutic target for metabolic disorders and the prevention of age-associated diseases. Thus the identification of compounds that modulate SIRT6 activity could be of great therapeutic importance. We have...
Alex K K Leung et al.
The journal of physical chemistry. B, 119(28), 8698-8706 (2015-06-19)
Previous work has shown that lipid nanoparticles (LNP) composed of an ionizable cationic lipid, a poly(ethylene glycol) (PEG) lipid, distearoylphosphatidylcholine (DSPC), cholesterol, and small interfering RNA (siRNA) can be efficiently manufactured employing microfluidic mixing techniques. Cryo-transmission electron microscopy (cryo-TEM) and...
Marco Costantini et al.
ACS applied materials & interfaces, 7(42), 23660-23671 (2015-10-06)
Ordered porous polymeric materials can be engineered to present highly ordered pore arrays and uniform and tunable pore size. These features prompted a number of applications in tissue engineering, generation of meta materials, and separation and purification of biomolecules and...

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