We have a long history of expertise and innovation in liquid chromatography. We have an extensive team of scientists who continuously develop new protocols, monographs, and research papers for HPLC, UHPLC, and LPLC. Our technical library contains numerous detailed protocols for quantifying specific analytes according to a variety of regulatory methods.
Small molecules are ions and compounds of molecular weight typically less than 900 daltons. These compounds can be effectively separated and analyzed by HPLC, UHPLC and LC-MS using mainly silica particles or monolithic stationary phases with a broad range of column chemistries (modifications).
High performance liquid chromatography (HPLC) can be used to separate and identify different large biomolecules such as protein and peptides in a sample. It is based on the pumping of a sample with a solvent (mobile phase) through a column packed with sorbent material (stationary phase) at a high pressure.
Low pressure liquid chromatography (LPLC) is a chromatographic technique that operates at low pressures to drive the mobile phase onto the column containing a stationary phase by the action of a pump.