299251

Sigma-Aldrich

Ammonium-15N chloride

≥98 atom % 15N, ≥99% (CP)

Synonym(s):
15N Labeled ammonium chloride
Linear Formula:
15NH4Cl
CAS Number:
Molecular Weight:
54.48
MDL number:
PubChem Substance ID:

isotopic purity

≥98 atom % 15N

Quality Level

assay

≥99% (CP)

application(s)

bio NMR: suitable
protein expression: suitable

mp

340 °C (subl.) (lit.)

mass shift

M+1

SMILES string

[15NH4+].[Cl-]

InChI

1S/ClH.H3N/h1H;1H3/i;1+1

InChI key

NLXLAEXVIDQMFP-IEOVAKBOSA-N

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Application

Ammonium-15N chloride has been used:
  • as a medium supplement for the incorporation of 15N in sporulation protein, CsfB, for NMR spectroscopy
  • in assaying nitrogen loss in marine sediment
  • for the incorporation of 15N in apolipoprotein A-I for mass spectrum analysis

Packaging

250 mg in glass insert
1, 10, 20, 50, 100 g in glass bottle
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

Biochem/physiol Actions

Ammonium chloride is a component of the nitrogen cycle. Excess of ammonium chloride depletes ATP in astrocytes. Ammonium chloride inhibits the acidification in endosome-lysosome system. It is a hemolysing agent used in the lysis of erythrocytes. Ammonium chloride administration promotes creatinine and urea clearance in rat.

pictograms

Exclamation mark

signalword

Warning

hazcat

Acute Tox. 4 Oral - Eye Irrit. 2

storage_class_code

11 - Combustible Solids

WGK Germany

WGK 1

Flash Point F

Not applicable

Flash Point C

Not applicable

Personal Protective Equipment

dust mask type N95 (US),Eyeshields,Gloves

Certificate of Analysis

Certificate of Origin

Brianna J Klein et al.
Structure (London, England : 1993), 28(1), 105-110 (2019-11-13)
The assembly of human histone acetyltransferase MOZ/MORF complexes relies on the scaffolding bromodomain plant homeodomain (PHD) finger 1 (BRPF1) subunit. The PHD-zinc-knuckle-PHD module of BRPF1 (BRPF1PZP) has been shown to associate with the histone H3 tail and DNA; however, the...
Anaerobic ammonium oxidation linked to sulfate and ferric iron reduction fuels nitrogen loss in marine sediments
Rios-Del T, et al.
Biodegradation, 29(5), 429-442 (2018)
Emergence of resistance to antibacterial agents: the role of quaternary ammonium compounds?a critical review
Buffet-Bataillon S, et al.
International Journal of Antimicrobial Agents, 39(5), 381-389 (2012)
Zhen-Zhen Zheng et al.
Nature communications, 11(1), 3511-3511 (2020-07-16)
In the context of continuously increasing anthropogenic nitrogen inputs, knowledge of how ammonia oxidation (AO) in the ocean responds to warming is crucial to predicting future changes in marine nitrogen biogeochemistry. Here, we show divergent thermal response patterns for marine...
Characterization of homodimer interfaces with cross-linking mass spectrometry and isotopically labeled proteins
Lima DB, et al.
Nature Protocols, 13(3), 431-431 (2018)
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