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Merck

743232

Sodium triflinate

≥95.0% (T)

Synonym(s):

Langlois reagent, Sodium trifluoromethanesulfinate, Sodium trifluoromethylsulfinate, Trifluoromethanesulfinic acid sodium salt

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2 G

460,00 kr

5 G

880,00 kr

25 G

2 760,00 kr

460,00 kr


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About This Item

Empirical Formula (Hill Notation):
CF3NaO2S
CAS Number:
Molecular Weight:
156.06
UNSPSC Code:
12352101
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3723394
Assay:
≥95.0% (T)
Form:
powder

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InChI

1S/CHF3O2S.Na/c2-1(3,4)7(5)6;/h(H,5,6);/q;+1/p-1

SMILES string

[Na+].[O-]S(=O)C(F)(F)F

InChI key

KAVUKAXLXGRUCD-UHFFFAOYSA-M

assay

≥95.0% (T)

form

powder

reaction suitability

reaction type: C-C Bond Formation

impurities

≤1.0% water (Karl Fischer)

mp

<325 °C

functional group

fluoro, sulfinic acid

Quality Level

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1 of 4

This Item
3679077144095710
assay

≥95.0% (T)

assay

98%

assay

≥99.0% (T)

assay

≥90% (T)

reaction suitability

reaction type: C-C Bond Formation

reaction suitability

-

reaction suitability

-

reaction suitability

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

100

form

powder

form

solid

form

flakes

form

powder

mp

<325 °C

mp

253-255 °C (lit.)

mp

>300 °C (lit.)

mp

-

impurities

≤1.0% water (Karl Fischer)

impurities

-

impurities

-

impurities

-

Application

Sodium triflinate (Langlois reagent) is a trifluoromethylating reagent[1] used to incorporate trifluoromethyl groups onto aromatic and heteroaromatic moieties.[2][3]

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Joachim Demaerel et al.
Ultrasonics sonochemistry, 41, 134-142 (2017-11-16)
Direct sonication by means of ultrasound horns constitutes a widely used technique in chemical process technology. However, the direct contact between the metal probe and the reaction mixture does not always leave the chemical system unaffected. In this report, we
Indrajit Ghosh et al.
Science (New York, N.Y.), 365(6451), 360-366 (2019-07-28)
Photoexcited electron-hole pairs on a semiconductor surface can engage in redox reactions with two different substrates. Similar to conventional electrosynthesis, the primary redox intermediates afford only separate oxidized and reduced products or, more rarely, combine to one addition product. Here
Yulia A Konik et al.
Organic & biomolecular chemistry, 15(21), 4635-4643 (2017-05-18)
Tertiary cyclopropanols easily available from carboxylic esters have been used in the synthesis of distally fluorinated ketones. Cyclopropane ring cleavage reactions in methanol with aqueous tert-butyl hydroperoxide in the presence of a copper(ii) acetate catalyst and sodium triflinate (Langlois reagent)
Innate CH trifluoromethylation of heterocycles.
Ji Y, et al.
Proceedings of the National Academy of Sciences of the USA, 108(35), 14411-14415 (2011)
Sodium Trifluoromethanesulfinate.
eEROS (Encyclopedia of Reagents for Organic Synthesis) (2014)

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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