81801

Propylphosphonic anhydride solution

technical, ~50% in DMF

• Synonym(s): 1-Propanephosphonic anhydride solution, 2,4,6-Tripropyl-1,3,5,2,4,6-trioxatriphosphorinane-2,4,6-trioxide solution, PPACA, T3P^®
• Empirical Formula (Hill Notation): C₉H₂₁O₆P₃
• CAS Number: 68957-94-8
• Molecular Weight: 318.18
• Beilstein: 5079255
• MDL number: MFCD00006583
• PubChem Substance ID: 57652890
• NACRES: NA.22

Properties

• grade: technical
• Quality Level: 100
• form: solution
• concentration: ~50% in DMF
• SMILES string: CCCP1(=O)OP(=O)(CCC)OP(=O)(CCC)O1
• InChI: 1S/C9H21O6P3/c1-4-7-16(10)13-17(11,8-5-2)15-18(12,14-16)9-6-3/h4-9H2,1-3H3
• InChI key: PAQZWJGSJMLPMG-UHFFFAOYSA-N

Description

General description

Propylphosphonic anhydride is a highly reactive cyclic anhydride that is commonly used as a coupling agent and water scavenger.

Application

Coupling reagent for peptide synthesis; Preparation of other amides; Synthesis of esters (depsipeptides)

Packaging

25, 100 mL in glass bottle

Features and Benefits

Some of its unique features include:

• Broad functional group tolerance
• Low epimerization tendency
• By-products are water-soluble
• High yield and purity

Legal Information

T3P is a registered trademark of Archimica GmbH

Safety Information

• Pictograms: GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H290 - H314 - H317 - H360D
• Precautionary Statements: P202 - P234 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): 143.6 °F
• Flash Point(C): 62 °C
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves