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810890P

Avanti

Fluorescent DOTAP

1-oleoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-3-trimethylammonium propane (chloride salt), powder

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Synonym(s):
18:1-06:0 NBD DOTAP
Empirical Formula (Hill Notation):
C36H60ClN5O7
CAS Number:
Molecular Weight:
710.34
NACRES:
NA.25

Assay

>99% (TLC)

form

powder

packaging

pkg of 1 × 50 μg (810890P-50ug)

manufacturer/tradename

Avanti Polar Lipids 810890P

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C12)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O.[Cl-]

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This Item
790326P810215P850153P
Fluorescent DOTAP 1-oleoyl-2-[6-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]hexanoyl]-3-trimethylammonium propane (chloride salt), powder

Avanti

810890P

Fluorescent DOTAP

C12-NBD Phytosphingosine N-[12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl]-phytosphingosine, powder

Avanti

810215P

C12-NBD Phytosphingosine

18:1 PI(3,4)P2 1,2-dioleoyl-sn-glycero-3-phospho-(1′-myo-inositol-3′,4′-bisphosphate) (ammonium salt), powder

Avanti

850153P

18:1 PI(3,4)P2

form

powder

form

powder

form

powder

form

powder

packaging

pkg of 1 × 50 μg (810890P-50ug)

packaging

pkg of 1 × 10 mg (790326P-10mg)

packaging

pkg of 1 × 50 μg (810215P-50ug)

packaging

pkg of 1 × 100 μg (with stopper and crimp cap (850153P-100ug)), pkg of 1 × 500 μg (with stopper and crimp cap (850153P-500ug))

manufacturer/tradename

Avanti Polar Lipids 810890P

manufacturer/tradename

Avanti Polar Lipids 790326P

manufacturer/tradename

Avanti Polar Lipids 810215P

manufacturer/tradename

Avanti Polar Lipids 850153P

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

N-(1-(2,3-dioleoyloxy)propyl)-N,N,N-trimethylammonium (DOTAP) is a cationic lipid, which forms strong complexes with DNA. It aids the cellular delivery of RNA and DNA. DOTAP acts as a transfection agent.

Application

Fluorescent DOTAP has been used for the preparation of liposomes loaded with gold and verteporfin (VP).

Packaging

2 mL Amber Serum Vial with Stopper and Crimp Cap (810890P-50ug)

Storage Class Code

11 - Combustible Solids


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Controlled gene and drug release from a liposomal delivery platform triggered by X-ray radiation
Deng W, et al.
Nature Communications, 9(1), 2713-2713 (2018)
Neurons: Methods and Applications for the Cell Biologist (2003)
Phospholipid-cationic lipid interactions: influences on membrane and vesicle properties
Campbell RB, et al.
Biochimica et Biophysica Acta - Biomembranes, 1512(1), 27-39 (2001)

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