880128P

DSPE-PEG(2000) Amine

Avanti Polar Lipids 880128P, powder

• Synonym(s): 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[amino(polyethylene glycol)-2000] (ammonium salt)
• CAS Number: 474922-26-4
• NACRES: NA.25

Properties

• form: powder
• packaging: pkg of 1 × 10 mg (880128P-10mg); pkg of 1 × 100 mg (880128P-100mg); pkg of 1 × 25 mg (880128P-25mg); pkg of 1 × 50 mg (880128P-50mg); pkg of 1 × 500 mg (880128P-500mg)
• manufacturer/tradename: Avanti Polar Lipids 880128P
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCCNC(OCCOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOOO/C=C\N)=O)=O)(OC(CCCCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.C=C.

Description

General description

DSPE-PEG(2000) is a 18-carbon acyl chain containing phospholipid with a critical micelle concentration of 1× 10⁶ M. It is conjugated with functional groups like biotin, primary amine and carboxylic acid. The micelles display spheroid shape with a size of 18mm.

Application

DSPE-PEG(2000) Amine has been used:

• for the generation of single-walled carbon nanotubes (SWNTs) phospholipid-polyethylene glycol-folic acid conjugate
• in the preparation of polyethylene glycol (PEGylated) magnetic nanoparticles based liposomes
• in the preparation of liposomes for myomerger ectodomain based disruption studies

Biochem/physiol Actions

DSPE-PEG(2000) micelles aids in the solubilization of hydrophobic drugs and their delivery. It is used for coating of magnetic iron oxide-based nanoparticles.

Packaging

20 mL Clear Glass Screw Cap Vial (880128P-500mg)

5 mL Amber Glass Screw Cap Vial (880128P-100mg)

5 mL Amber Glass Screw Cap Vial (880128P-10mg)

5 mL Amber Glass Screw Cap Vial (880128P-25mg)

5 mL Amber Glass Screw Cap Vial (880128P-50mg)

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3