Merck
All Photos(1)

Documents

890705P

Avanti

16:0-18:1 EPC (Cl Salt)

Avanti Polar Lipids 890705P, powder

Synonym(s):
1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt)
Empirical Formula (Hill Notation):
C44H87NO8PCl
CAS Number:
Molecular Weight:
824.59
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 10 mg (890705P-10mg)
pkg of 1 × 25 mg (890705P-25mg)

manufacturer/tradename

Avanti Polar Lipids 890705P

application(s)

advanced drug delivery

lipid type

transfection
cationic lipids

shipped in

dry ice

storage temp.

−20°C

SMILES string

O=P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O)OCC.[Cl-]

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
890705C890704P890702P
16:0-18:1 EPC (Cl Salt) Avanti Polar Lipids 890705P, powder

Avanti

890705P

16:0-18:1 EPC (Cl Salt)

16:0-18:1 EPC (Cl Salt) Avanti Polar Lipids 890705C

Avanti

890705C

16:0-18:1 EPC (Cl Salt)

18:1 EPC (Cl Salt) Avanti Polar Lipids

Avanti

890704P

18:1 EPC (Cl Salt)

16:0 EPC (Cl Salt) Avanti Polar Lipids 890702P, powder

Avanti

890702P

16:0 EPC (Cl Salt)

packaging

pkg of 1 × 10 mg (890705P-10mg), pkg of 1 × 25 mg (890705P-25mg)

packaging

pkg of 1 × 1 mL (890705C-10mg), pkg of 1 × 2.5 mL (890705C-25mg)

packaging

pkg of 1 × 100 mg (890704P-100mg), pkg of 2 × 100 mg (890704P-200mg), pkg of 1 × 25 mg (890704P-25mg)

packaging

pkg of 1 × 10 mg (890702P-10mg), pkg of 1 × 100 mg (890702P-100mg)

manufacturer/tradename

Avanti Polar Lipids 890705P

manufacturer/tradename

Avanti Polar Lipids 890705C

manufacturer/tradename

Avanti Polar Lipids

manufacturer/tradename

Avanti Polar Lipids 890702P

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

application(s)

advanced drug delivery

application(s)

-

application(s)

-

application(s)

-

General description

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is cationic lipid containing an ethyl group attached to the phosphate moiety through an ester bond and has a choline headgroup.

Application

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (chloride salt) (16:0-18:1 EPC (Cl Salt)) might be used:
  • as a cationic lipid to explore the change in organization and dynamics of a membrane-bound fluorescent probe in host membranes of varying charge
  • in the preparation of small unilamellar cationic liposomes
  • in a novel albumin-associated lipoplex formulation to evaluate the antitumoral efficacy of immuno-gene therapy and “suicide” gene therapy

Biochem/physiol Actions

1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (16:0-18:1 EPC) is a potential transfection agent, which is also similar to the natural lipids.

Packaging

5 mL Clear Glass Sealed Ampule (890705P-10mg)
5 mL Clear Glass Sealed Ampule (890705P-25mg)

Storage Class Code

11 - Combustible Solids


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (Example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Marta Passadouro et al.
International journal of nanomedicine, 9, 3203-3217 (2014-07-26)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive and mortal cancer, characterized by a set of known mutations, invasive features, and aberrant microRNA expression that have been associated with hallmark malignant properties of PDAC. The lack of effective PDAC treatment
Modulation of fluorophore environment in host membranes of varying charge
Kelkar DA, et al.
Journal of Fluorescence, 13(6), 459-466 (2003)
H Faneca et al.
Biochimica et biophysica acta, 1768(5), 1093-1102 (2007-02-14)
In the present work, we used a novel albumin-associated lipoplex formulation, containing the cationic lipid 1-palmitoyl-2-oleoyl-sn-glycero-3-ethylphosphocholine (EPOPC) and cholesterol (Chol), to evaluate the antitumoral efficacy of two gene therapy strategies: immuno-gene therapy, mediated by IL-12 gene expression, and "suicide" gene
Wei Zong et al.
Langmuir : the ACS journal of surfaces and colloids, 34(23), 6874-6886 (2018-05-20)
The success of nanoparticulate formulations in drug delivery depends on various aspects including their toxicity, internalization, and intracellular location. Vesicular assemblies consisting of phospholipids and amphiphilic block copolymers are an emerging platform, which combines the benefits from liposomes and polymersomes
Li Wang et al.
Molecular pharmaceutics, 4(4), 615-623 (2007-04-06)
To date, the primary approach to improving the transfection properties of cationic lipids has been the synthesis of new kinds of cationic amphipaths. Recently, however, it was found that combining two cationic lipid derivatives having the same head group but

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service