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890860P

Avanti

14:0 TAP

Avanti Polar Lipids 890860P, powder

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Synonym(s):
1,2-dimyristoyl-3-trimethylammonium-propane (chloride salt)
Empirical Formula (Hill Notation):
C34H68NO4Cl
CAS Number:
197974-74-6
Molecular Weight:
590.36
NACRES:
NA.25

form

powder

packaging

pkg of 1 × 200 mg (890860P-200mg)

manufacturer/tradename

Avanti Polar Lipids 890860P

lipid type

cationic lipids
transfection

shipped in

dry ice

storage temp.

−20°C

SMILES string

[H]C(C[N+](C)(C)C)(OC(CCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCC)=O.[Cl-]

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This Item
890860C890870P890880P
14:0 TAP Avanti Polar Lipids 890860P, powder

Avanti

890860P

14:0 TAP

14:0 TAP Avanti Polar Lipids 890860C

Avanti

890860C

14:0 TAP

16:0 TAP Avanti Polar Lipids 890870P, powder

Avanti

890870P

16:0 TAP

18:0 TAP Avanti Polar Lipids 890880P, powder

Avanti

890880P

18:0 TAP

packaging

pkg of 1 × 200 mg (890860P-200mg)

packaging

pkg of 1 × 2.5 mL (890860C-25mg), pkg of 2 × 4 mL (890860C-200mg)

packaging

pkg of 1 × 200 mg (890870P-200mg), pkg of 1 × 25 mg (890870P-25mg), pkg of 1 × 500 mg (890870P-500mg)

packaging

pkg of 1 × 200 mg (890880P-200mg), pkg of 1 × 25 mg (890880P-25mg)

manufacturer/tradename

Avanti Polar Lipids 890860P

manufacturer/tradename

Avanti Polar Lipids 890860C

manufacturer/tradename

Avanti Polar Lipids 890870P

manufacturer/tradename

Avanti Polar Lipids 890880P

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

lipid type

cationic lipids
transfection

lipid type

cationic lipids
transfection

lipid type

transfection
cationic lipids

lipid type

cationic lipids
transfection

General description

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is a saturated cationic lipid with a positively charged headgroup. It has an alkyl chain length with 14 carbon atoms.

Application

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is suitable for:
  • the preparation of cationic liposomes
  • reconstitution of bacteriorhodopsin (BR) and proteorhodopsin (PR) into liposomes
  • composing lipid–styrene maleic acid (SMA) complexes
  • liposome preparation by double emulsion method

Biochem/physiol Actions

1,2-dimyristoyl-3-trimethylammonium-propane (14:0 TAP) is useful for bicelle formation. Bicelles can be integrated into standard crystallization protocols, and in contrast to micelles, bicelles maintain the protein in a more native bilayer environment allowing proteins to be captured in a more biologically relevant orientation.

Packaging

5 mL Amber Glass Screw Cap Vial (890860P-200mg)

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

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Lipid-induced dynamics of photoreceptors monitored by time-resolved step-scan FTIR spectroscopy
Jawurek M, et al.
Chemical Physics, 512, 53-61 (2018)
Masafumi Tanaka et al.
Biochimica et biophysica acta. Biomembranes, 1862(5), 183209-183209 (2020-02-01)
Styrene maleic acid copolymers (SMA) form discoidal lipid nanoparticles (lipid nanodisks) that mimic plasma high-density lipoproteins. We have previously prepared and characterized lipid nanodisks composed of SMA and the neutral phospholipid 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC). In the present study, we tested whether
Reverse osmosis membranes based on a supported lipid bilayer with gramicidin A water channels
Saeki D, et al.
Desalination, 375, 48-53 (2015)
Nishu Kanwa et al.
Physical chemistry chemical physics : PCCP, 22(6), 3234-3244 (2020-01-30)
In the present contribution, we investigate the interactions of lipid bilayer membranes of different charges and different phase states with aliphatic amino acids of varying charge (aspartic acid, glutamic acid, arginine and lysine) and hydrophobicity (serine, leucine and valine) by
A E Regelin et al.
Biochimica et biophysica acta, 1464(1), 151-164 (2000-03-08)
In order to investigate the relationship between lipid structure and liposome-mediated gene transfer, we have studied biophysical parameters and transfection properties of monocationic DOTAP analogs, systematically modified in their non-polar hydrocarbon chains. Stability, size and (by means of anisotropy profiles)
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