09658

Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate

≥98.0% (T)

• Synonym(s): TCFH
• Empirical Formula (Hill Notation): C₅H₁₂ClF₆N₂P
• CAS Number: 207915-99-9
• Molecular Weight: 280.58
• Beilstein: 7896715
• MDL number: MFCD01862891
• PubChem Substance ID: 329748788
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥98.0% (T)
• reaction suitability: reaction type: Coupling Reactions
• mp: 99-108 °C
• application(s): peptide synthesis
• storage temp.: 2-8°C
• SMILES string: F[P-](F)(F)(F)(F)F.CN(C)\C(Cl)=[N+](\C)C
• InChI: 1S/C5H12ClN2.F6P/c1-7(2)5(6)8(3)4;1-7(2,3,4,5)6/h1-4H3;/q+1;-1
• InChI key: CUKNPSDEURGZCO-UHFFFAOYSA-N

Description

Application

Chloro-N,N,N′,N′-tetramethylformamidinium hexafluorophosphate can be used as a reactant for the synthesis of:

• Onium salts for use in peptide coupling.
• Benzotriazole based uranium reagent, a safer replacement for coupling reagents.

It can also be used as a reagent for the synthesis of:

• Cancer cell cytotoxins.
• Bioconjugation reagents.

Other Notes

Coupling reagent for peptide synthesis and starting material for preparing other coupling reagents

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves