O1875

Orcinol monohydrate

colorimetric detection reagent

• Synonym(s): 3,5-Dihydroxytoluene, 5-Methylresorcinol
• Linear Formula: CH₃C₆H₃-1,3-(OH)₂ · H₂O
• CAS Number: 6153-39-5
• Molecular Weight: 142.15
• Beilstein: 1071903
• EC Number: 207-984-2
• MDL number: MFCD00149092
• PubChem Substance ID: 24897953
• NACRES: NA.47

Properties

• biological source: synthetic
• Quality Level: 200
• Assay: ≥99% (HPLC)
• form: powder
• bp: 290 °C (lit.)
• mp: 56-58 °C (lit.)
• solubility: H₂O: 50 mg/mL
• density: 1.290 g/cm³
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: O.Cc1cc(O)cc(O)c1
• InChI: 1S/C7H8O2.H2O/c1-5-2-6(8)4-7(9)3-5;/h2-4,8-9H,1H3;1H2
• InChI key: NBKPNAMTHBIMLA-UHFFFAOYSA-N

Description

General description

Orcinol is a small-molecule natural phenol involved in the production of a dye called orcein used for the staining of cells and chromosomes. Orcinol monohydrate is usually used to prepare a colorimetric reagent known as Bial′s reagent for the determination of RNA, DNA, and hexoses.

Application

Orcinol monohydrate has been used to prepare Bial′s reagent for Bial′s orcinol assay for pentose sugars. It is also used in the preparation of orcinol solution suitable for staining TLC plates and, measuring rhamnolipids in orcinol dye assays. Orcinol monohydrate has been used for the RNA assay.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302 - H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves