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S1429

Sigma-Aldrich

Sodium acetate

meets USP testing specifications, anhydrous

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Synonym(s):
Acetic acid sodium salt
Linear Formula:
CH3COONa
CAS Number:
Molecular Weight:
82.03
Beilstein:
3595639
EC Number:
MDL number:
eCl@ss:
39021906
PubChem Substance ID:
NACRES:
NA.21

grade

anhydrous

Quality Level

Agency

USP/NF
meets USP testing specifications

Assay

99-101% dry basis

form

solid

autoignition temp.

1112 °F

pH

8.5-9.9 (25 °C, 246 g/L)

pKa 

4.76 (acetic acid)

mp

>300 °C (dec.) (lit.)

solubility

soluble 246 g/L at 20 °C (completely)

application(s)

pharmaceutical (small molecule)

SMILES string

[Na+].CC([O-])=O

InChI

1S/C2H4O2.Na/c1-2(3)4;/h1H3,(H,3,4);/q;+1/p-1

InChI key

VMHLLURERBWHNL-UHFFFAOYSA-M

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S754571183S5636
Sodium acetate meets USP testing specifications, anhydrous

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Premium Grade
Sodium acetate powder, BioReagent, suitable for electrophoresis, suitable for cell culture, suitable for insect cell culture, ≥99%

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Essential+ Grade
agency

USP/NF, meets USP testing specifications

agency

-

agency

-

agency

-

assay

99-101% dry basis

assay

≥99.0%

assay

≥99.0% (NT)

assay

≥99%

form

solid

form

solid

form

solid

form

powder, solid

pH

8.5-9.9 (25 °C, 246 g/L)

pH

8.5-9.9 (25 °C, 246 g/L)

pH

8.5-10.0 (25 °C, 3 M in H2O)

pH

8.9 (25 °C, 100 mg/mL in water, 0.1 M agueous sodium acetate solution)

mp

>300 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

mp

>300 °C (dec.) (lit.)

General description

Sodium acetate (SA) exhibits antimicrobial and antioxidant properties. It is used as an exchange-fluid buffer in hemodialysis. SA acts as an a alkalinizing agent and its continuous intravenous (IV) infusion causes salicylate intoxication.

Application

Sodium acetate (SA) has been used to increase hepatic acetyl- coenzyme A in caloric restricted rats.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Mechanisms by which a very-low-calorie diet reverses hyperglycemia in a rat model of type 2 diabetes
Perry RJ, et al.
Cell Metabolism, 27(1), 210-217 (2018)
Sodium Acetate as an Alkalinizing Agent for Salicylate Intoxication: A Case Report
Groke SF, et al.
Journal of Clinical Toxicology (2015)
Antimicrobial and antioxidant effects of sodium acetate, sodium lactate, and sodium citrate in refrigerated sliced salmon
Sallam KI, et al.
Food Control, 18(5), 566-575 (2007)
Enhancement of in-vitro human interleukin-1 production by sodium acetate
Bingel M, et al.
Lancet, 329(8523), 14-16 (1987)
Amanda P De Souza et al.
Journal of experimental botany, 66(14), 4351-4365 (2015-04-25)
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