C9008

p-Coumaric acid

≥98.0% (HPLC)

• Synonym(s): trans-4-Hydroxycinnamic acid
• Linear Formula: HOC₆H₄CH=CHCO₂H
• CAS Number: 501-98-4
• Molecular Weight: 164.16
• Beilstein: 2207383
• MDL number: MFCD00004399
• PubChem Substance ID: 24893127
• NACRES: NA.47

Properties

• Quality Level: 200
• Assay: ≥98.0% (HPLC)
• form: powder
• mp: 214 °C (dec.) (lit.)
• solubility: ethanol: 50 mg/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: OC(=O)\C=C\c1ccc(O)cc1
• InChI: 1S/C9H8O3/c10-8-4-1-7(2-5-8)3-6-9(11)12/h1-6,10H,(H,11,12)/b6-3+
• InChI key: NGSWKAQJJWESNS-ZZXKWVIFSA-N

Description

Application

p-Coumaric acid has been used as a component of chemiluminescent substrate for protein detection in western blotting.

Biochem/physiol Actions

p-Coumaric acid is mainly a plant metabolite which exhibits antioxidant and anti-inflammatory properties. It also shows bactericidal activity by damaging bacterial cell membrane and by interacting with bacterial DNA. In western blot, p-coumaric is also used as an enhancer in chemiluminescent substrate.

Hydroxycinnamic acid found in many fruits and vegetables.

Other Notes

Predominantly trans isomer.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves