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P7539

Sigma-Aldrich

Penicillin–Streptomycin Solution Hybri-Max

with 10,000 units penicillin and 10mg/ml streptomycin in 0.9% NaCl, 0.1 μm filtered, BioReagent, suitable for hybridoma

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Synonym(s):
Pen-Strep

Quality Level

sterility

0.1 μm filtered

product line

BioReagent

form

liquid

technique(s)

cell culture | hybridoma: suitable

impurities

endotoxin, tested

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell wall synthesis | interferes
protein synthesis | interferes

shipped in

dry ice

storage temp.

−20°C

Related Categories

General description

Penicillin-Streptomycin is used to supplement cell culture media to control bacterial contamination.

Application

Penicillin–Streptomycin Solution Hybri-Max has been used:
  • as a supplement in Roswell Park Memorial Institute (RPMI) 1640 medium to maintain human breast cancer cell lines
  • as a component of the Dulbecco′s modified Eagle′s medium/F-12 (DMEM/F-12) to culture human chondrocytes
  • as a component of the DMEM medium to culture human hepatocyte carcinoma cells

Other Notes

20ml,100ml
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Chun-Yen Sung et al.
Biofabrication, 7(4), 045007-045007 (2015-12-20)
In this study, we describe the development of surface-modified chitosan substrates to examine topographically related Neuro-2a cell behaviors. Different functional groups can be modified on chitosan surfaces to probe Neuro-2a cell morphology. To prepare chitosan substrates with micro/nano-scaled features, we
Soumalya Sarkar et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 144, 112357-112357 (2021-11-20)
Higher global prevalence of non-alcoholic fatty liver disease (NAFLD) is associated with obesity, steatosis, and insulin resistance (IR), and often progresses to steatohepatitis (NASH). Even after more than twenty years of research, there is still no FDA approved therapy for
Edda Blümel et al.
Oncoimmunology, 9(1), 1751561-1751561 (2020-05-05)
Staphylococcus aureus and its toxins have been linked to disease progression and mortality in advanced stages of cutaneous T-cell lymphoma (CTCL). CD8+ T cells play a crucial role in anti-cancer responses and high CD8+ T cell numbers in tumor lesions
Casper Bindzus Foldager et al.
Cartilage, 7(1), 52-61 (2016-03-10)
To identify the collagen type IV (Col4) isoform in articular cartilage and to evaluate the expressions of Col4 and laminin in the pericellular matrix (PCM) in damaged cartilage and during cartilage repair. The Col4 isoform was determined in chondrocytes isolated
Jessica Roos et al.
Antioxidants & redox signaling, 28(14), 1265-1285 (2017-07-13)
5-Lipoxygenase (5-LO) is the key enzyme of leukotriene (LT) biosynthesis and is critically involved in a number of inflammatory diseases such as arthritis, gout, bronchial asthma, atherosclerosis, and cancer. Because 5-LO contains critical nucleophilic amino acids, which are sensitive to

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