T1147

apo-Transferrin human

powder, BioReagent, suitable for cell culture, ≥98% (agarose gel electrophoresis)

• Synonym(s): Human transferrin, Siderophilin
• CAS Number: 11096-37-0
• EC Number: 234-318-8
• MDL number: MFCD00130536
• NACRES: NA.75

Properties

• biological source: human plasma
• Quality Level: 200
• product line: BioReagent
• Assay: ≥98% (agarose gel electrophoresis)
• form: powder
• mol wt: 76-81 kDa
• concentration: ~25 mM
• technique(s): cell culture | mammalian: suitable
• impurities: HIV and HBsAg, source material tested negative; ≤0.005% iron
• solubility: H₂O: 50 mg/mL
• UniProt accession no.: P02787
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... TF(7018)

Description

Application

Apo-Transferrin human can be supplemented with iron or used to bind free iron present in media. It is also used to transport iron into mammalian cells.

Biochem/physiol Actions

Transferrin is the primary iron binding and cell delivery molecule present in serum. Serum-free cell culture systems require a delivery format for iron. Transferrin is the preferential delivery form of iron because cells process transferrin bound iron in a physiologically appropriate way through transferrin receptors on the cell surface. Human apo-transferrin is a high affinity transferrin that can be used with a wide range of cells types. Apo-transferrin can be loaded with iron prior to use or added directly to an iron containing medium.

Other Notes

Non-heme iron-transport protein.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3