Merck
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1706698

USP

Urea

United States Pharmacopeia (USP) Reference Standard

Synonym(s):
Carbamide, Carbonyldiamide
Linear Formula:
NH2CONH2
CAS Number:
Molecular Weight:
60.06
Beilstein:
635724
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

urea

manufacturer/tradename

USP

mp

132-135 °C (lit.)

density

1.335 g/mL at 25 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

15-25°C

SMILES string

NC(N)=O

InChI

1S/CH4N2O/c2-1(3)4/h(H4,2,3,4)

InChI key

XSQUKJJJFZCRTK-UHFFFAOYSA-N

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U0600000BP3501.08432
Urea United States Pharmacopeia (USP) Reference Standard

USP

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U0600000

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Urea British Pharmacopoeia (BP) Reference Standard

BP350

Urea

Urea crystalline, EMPROVE® API, Ph. Eur., BP, USP

SAFC

1.08432

Urea

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

grade

GMO free, GMP, Halal, Kosher

manufacturer/tradename

USP

manufacturer/tradename

EDQM

manufacturer/tradename

BP

manufacturer/tradename

-

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

-

application(s)

ophthalmics
pharmaceutical
semi-solid formulation

format

neat

format

neat

format

neat

format

-

API family

urea

API family

urea

API family

urea

API family

-

mp

132-135 °C (lit.)

mp

132-135 °C (lit.)

mp

132-135 °C (lit.)

mp

132-135 °C (lit.)

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Urea USP reference standard for use in specified quality tests and assays.

Also used to prepare standard, urea standard stock, and system suitability solutions for assay, and impurity analysis according to given below monographs of the United States Pharmacopeia (USP):
  • Urea
  • Fluorouracil
  • Allantoin
Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

USP issued SDS can be found here.
Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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