Our clarification portfolio provides flexibility to the biopharma manufacturer for efficient cell, cellular debris and other insoluble contaminant removal and impurity clearance from different process streams from process development through large-scale manufacturing. Millistak+®, Millistak+® HC Pro and Clarisolve® Depth filters are available in Pod devices.
Millistak+® HC Pro Filters
These are high capacity fully synthetic depth filters for primary and secondary clarification and downstream polishing applications.
Millistak+® Depth Filters
These filters are offered in both Pod and lenticular formats.
Clarisolve® depth filters offer a gradient density structure designed for efficient primary clarification of pretreated cell culture harvests.
Complementing our product portfolio, the Emprove® Program provides three types of dossiers to support different stages of development and manufacturing operations such as qualification, risk assessment, and process optimization. The dossiers consolidate comprehensive product-specific testing data, quality statements, and regulatory information in a readily available format to simplify your compliance needs.
Data Sheet: Millistak+® HC Pro Synthetic Depth Filters
Data Sheet: Millistak+® Pod Carbon Depth Filter Media System
Data Sheet: Clarification Solutions for Pre-treated Feed Streams
Data Sheet: Millistak+® Pod Disposable Depth Filter System
Chart: Millistak+® Filter Chemical Compatibility
Article: Generic Process of Virus-Like Particle (VLP) Based Vaccine Manufacturing
Article: Complete Clarification Solution for Processing High Density Cell Culture
Article: Selection of Clarification Methods for Improved Downstream Performance and Economics
Article: Evolving Clarification Strategies to Meet New Challenges
Article: Industrial Application of Impurity Flocculation to Streamline Antibody Purification Processes
Article: Development of a Novel and Efficient Cell Culture Flocculation Process Using a Stimulus Responsive Polymer to Streamline Antibody Purification Processes
Guide: Millistak+® Pod Disposable Depth Filter Performance
Application Note: Millistak+® Activated Carbon for mAb Downstream Purification
Application Note: pDADMAC Flocculant Reagent for Use with Clarisolve® Depth Filters
User Guide: Pod Depth Filters
User Guide: μPod® Filters
How to standardize the process development approach for a two-step clarification process ensuring development of a robust, scalable unit operation.
pDADMAC for pretreatment of mammalian cell culture harvest utilizing Clarisolve® depth filters for improved primary & secondary clarification of flocculated feeds.
Join to hear case studies on effective separation of host cell proteins (HCPs), antibody fragments and low molecular weight substances from solutions containing mAbs.