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Showing 1-30 of 111 results for "88-89-1" within Papers
Leila Noetzli et al.
Gene, 533(1), 447-450 (2013-10-10)
Hereditary spastic paraplegia (HSP) type 2 is a proteolipid protein (PLP1)-related genetic disorder that is characterized by dysmyelination of the central nervous system resulting primarily in limb spasticity, cognitive impairment, nystagmus, and spastic urinary bladder of varying severity. Previously reported
Zhibo Yang et al.
The Journal of biological chemistry, 280(1), 654-659 (2004-10-27)
Recent studies have identified dynein light chain-1 (DLC1), a component of the dynein motor, as a p21-activated kinase 1 (Pak1)-interacting substrate with binding sites mapped to amino acids 61-89 of DLC1 and phosphorylation site at serine 88. Here we investigated
Dominik Naessens et al.
Thrombosis and haemostasis, 90(1), 52-58 (2003-07-24)
The monoclonal antibody MA-33B8, directed against the serpin plasminogen activator inhibitor-1 (PAI-1), has unique functional properties as it induces acceleration of the active-to-latent transition (Verhamme I et al. J Biol Chem 274: 17511-7, 1999), resulting in PAI-1 activity neutralization. In
C G Plugariu et al.
Biochemistry, 39(48), 14939-14949 (2000-12-02)
Multisite mutagenesis of single-chain and monomeric forms of human interleukin 5 (IL-5) was performed to investigate mechanistic features of receptor activation and the possibility of differentiating sites of activation from those for receptor interaction. The normally dimeric human IL-5 contains
R B Fritz et al.
Journal of immunology (Baltimore, Md. : 1950), 134(4), 2328-2332 (1985-04-01)
Recent experiments have shown that different regions of myelin basic protein (MBP) are encephalitogenic for different inbred strains of mice. It was therefore of interest to determine whether the immune response to MBP was MHC associated, and if so, what
Angelo Di Leo et al.
The Lancet. Oncology, 12(12), 1134-1142 (2011-09-16)
Prediction of response to anthracycline-based therapy for breast cancer is challenging. We aimed to assess the value of HER2 and TOP2A as predictive markers of response to anthracycline-based adjuvant therapy in patients with early breast cancer. We did a meta-analysis
Teresa S Gross et al.
Pediatric research, 81(3), 461-467 (2016-11-10)
The health implications of in utero alcohol exposure have been difficult to study in very-low-birth-weight newborns (VLBW) because of an inability to identify maternal alcohol exposure. Fatty acid ethyl esters (FAEEs) are elevated in meconium of alcohol-exposed term newborns. We
Naoko Ishiguro et al.
Human pathology, 39(11), 1673-1679 (2008-07-29)
Cardiac ankyrin repeat protein (CARP) is highly expressed in cardiac muscles and detectable in normal skeletal muscles. Arpp, a close homolog of CARP, has been demonstrated to be useful for distinguishing rhabdomyosarcoma from other malignant tumors. However, the CARP distributions
H Zejli et al.
Talanta, 185, 513-519 (2018-05-16)
This work demonstrates the development of electrochemical aptasensor using ochratoxin A (OTA) aptamers. Different aptamer coupling strategies were tested using polythiophene-carboxylic acid (PT3C) and polypyrrole-3-carboxylic acid (PP3C). The best sensitivity was recorded by polythiophene-3-carboxylic acid (PT3C) on screen-printed carbon electrode
Bert Vanmechelen et al.
Scientific reports, 8(1), 11171-11171 (2018-07-26)
The family Arteriviridae harbors a rapidly expanding group of viruses known to infect a divergent group of mammals, including horses, pigs, possums, primates, and rodents. Hosts infected with arteriviruses present with a wide variety of (sub) clinical symptoms, depending on
Takao Hiraki et al.
BioMed research international, 2014, 152087-152087 (2014-07-06)
This review examines studies of radiofrequency ablation (RFA) of nonsmall cell lung cancer (NSCLC) and discusses the role of RFA in treatment of early-stage NSCLC. RFA is usually performed under local anesthesia with computed tomography guidance. RFA-associated mortality, while being
Palanisamy Kanmani et al.
Biotechnology progress, 31(5), 1249-1258 (2015-06-03)
Biological treatment of oil and grease (O&G)-containing industrial effluents has long been a challenging issue. Practically feasible avenues to bring down their O&G load and enhance treatability are desired. In one such endeavour, the partially purified lipase from Staphylococcus pasteuri
Molecular cloning and characterization of the germ cell-related nuclear orphan receptor in chickens.
Sang In Lee et al.
Molecular reproduction and development, 77(3), 273-284 (2009-12-19)
Nuclear receptor subfamily 6, group A, member 1 (NR6A1), also known as germ cell nuclear factor/retinoid receptor-related testis-associated receptor and neuronal cell nuclear factor, is a member of the nuclear orphan receptor superfamily. NR6A1 has been cloned in various species
W Yang et al.
DNA sequence : the journal of DNA sequencing and mapping, 12(4), 239-251 (2002-03-28)
The actions of platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) are mediated through the PAF receptor (PAFr), which is a member of G-protein coupled superfamily of receptors. Our laboratory has data showing PAF has a role(s) in reproduction in domestic animals. Porcine, bovine
Ulrich Mahlknecht et al.
Journal of leukocyte biology, 83(3), 718-727 (2007-12-12)
HIV-1 two-exon transactivator protein (Tat) is a 101-aa protein. We investigated the possible contribution of the extreme C terminus of HIV-1 Tat to maximize nuclear transcription factor NF-kappaB activation, long terminal repeat (LTR) transactivation, and viral replication in T cells.
F F Vajdos et al.
Protein science : a publication of the Protein Society, 6(11), 2297-2307 (1998-02-12)
The cellular protein, cyclophilin A (CypA), is incorporated into the virion of the type 1 human immunodeficiency virus (HIV-1) via a direct interaction with the capsid domain of the viral Gag polyprotein. We demonstrate that the capsid sequence 87His-Ala-Gly-Pro-Ile-Ala92 (87HAGPIA92)
S M Thompson et al.
Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 25(1), 108-111 (2016-08-06)
Injury to the proximal hamstring complex (PHC) is becoming more frequently diagnosed. Patients attending our tertiary referral centre demonstrated 'pathological changes' in the unaffected normal contralateral PHC on MRI. The prevalence of PHC pathology, however, has not been previously documented
M D Roper et al.
Mammalian genome : official journal of the International Mammalian Genome Society, 7(10), 754-757 (1996-10-01)
We have isolated and characterized a genomic fragment encompassing the first six exons and 2.6 kbp 5' flanking sequence of the rat cystathionine beta-synthase (CBS) gene. A previously unknown exon approximately 3 kbp upstream of exon 1 was identified. The
Ching-Yao Yang et al.
Cancer biomarkers : section A of Disease markers, 21(1), 211-220 (2017-10-19)
Globo H is a tumor-associated carbohydrate antigen exclusively expressed in cancer cells rather than normal tissue. Globo H has been found on many cancers of epithelial origins, and become an attractive target for cancer vaccine. We aimed to study the
Hiroyuki Nakai et al.
Carbohydrate research, 345(8), 1061-1064 (2010-04-16)
Lactobacillus acidophilus NCFM maltose phosphorylase (LaMalP) of glycoside hydrolase family 65 catalysed enzymatic synthesis of alpha-(1-->4)-glucosidic disaccharides from maltose and five monosaccharides in a coupled phosphorolysis/reverse phosphorolysis one-pot reaction. Thus phosphorolysis of maltose to beta-glucose 1-phosphate circumvented addition of costly
Monica Else et al.
Leukemia & lymphoma, 52 Suppl 2, 75-78 (2011-04-21)
The purine analogs pentostatin and cladribine are effective treatments for hairy cell leukemia (HCL). However, alternative treatments are needed for patients with recurrent disease. We reviewed retrospectively data from 18 patients who were retreated with either pentostatin (n = 12) or cladribine
M A M Harfoush et al.
Journal of the Egyptian Society of Parasitology, 40(2), 377-382 (2011-01-21)
The occurrence of resistance to three of commonly used anthelmintics, Pyrantel tartrate (Banminth), Albendazole2.5% (Valbazen) and Duramectin 1% (Dectomax) was studied in locally bred sheep in Kafr El Sheikh Governorate, Egypt, by means of faecal egg count reduction test (FECRT).
Reza Farzinebrahimi et al.
Evidence-based complementary and alternative medicine : eCAM, 2016, 6429652-6429652 (2016-06-15)
Leaf, seed, and tuber explants of C. latifolia were inoculated on MS medium supplemented with various concentrations of BAP and IBA, alone or in combinations, to achieve in vitro plant regeneration. Subsequently, antioxidant and antibacterial activities were determined from in
Christian Moberg et al.
Reproductive sciences (Thousand Oaks, Calif.), 17(6), 590-611 (2010-04-03)
The changes in transcript profile induced by vascular endothelial growth factor (VEGF-A) and serum withdrawal in primary human endometrial endothelial cells (ECs) were investigated using microarrays, gene ontology and pathway analysis. Vascular endothelial growth factor A altered the levels of
Yuko Oya et al.
Oncotarget, 8(61), 103117-103128 (2017-12-22)
Nivolumab offers a superior survival benefit over docetaxel in patients with advanced, previously treated non-small-cell lung cancer (NSCLC). An association between programmed cell death ligand-1 (PD-L1) expression and the efficacy of nivolumab has been reported in many studies. However, the
F M Dautzenberg et al.
Journal of neuroendocrinology, 11(12), 941-949 (1999-12-03)
Three full-length cDNAs encoding functional splice variants of the pituitary adenylate cyclase-activating polypeptide (PACAP) type 1 receptor (PAC1) were isolated from Y-79 retinoblastoma cells and human cerebellum. Although the third intracellular loops of the three splice variants were identical, their
J M McCarty
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 13(10), 846-850 (1994-10-01)
Cefprozil is a new oral cephalosporin with an enhanced in vitro spectrum of activity that includes group A beta-hemolytic streptococci (GABHS). Four multicenter randomized clinical trials were conducted to compare the clinical efficacy and safety of cefprozil administered once or
Yongqiang Li et al.
PloS one, 8(6), e66251-e66251 (2013-06-19)
Insecticidal activity of NK-17 was evaluated both in laboratory and in field. It was found that the toxicity of NK-17 against S. exigua was 1.93 times and 2.69 times those of hexaflumuron and chlorfluazuron respectively, and the toxicity of NK-17
Hyun-Chul Kim et al.
Water research, 89, 222-231 (2015-12-23)
In this study, we integrated physicochemical and biological strategies for the robust treatment of piggery effluent in which high levels of organic constituents, inorganic nutrients, color, and salts remained. Piggery effluent that was stabilized in an anaerobic digester was sequentially
Maria Honkavuori-Toivola et al.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 33(4), 935-941 (2012-01-25)
Tissue inhibitors of metalloproteinases are important regulators of metalloproteinase activity, and the balance of active enzyme and inhibitor is a critical determinant of tumor cell invasiveness. This study aimed to evaluate the prognostic and clinical implications of the two main
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