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D M Bernstein et al.
Toxicology and applied pharmacology, 387, 114856-114856 (2019-12-15)
This 90-day repeated-dose inhalation toxicology study of brake-dust (BD) (brakes manufactured with chrysotile) in rats provides a comprehensive understanding of the biokinetics and potential toxicology in the lung and pleura. Exposure was 6 h/d, 5d/wk., 13wks followed by lifetime observation (~20...
Jianing Yue et al.
Life sciences, 253, 117533-117533 (2020-03-11)
Abdominal aortic aneurysm (AAA) is featured by the growth impediment and apoptosis surge of VSMCs (vascular smooth muscle cells). MicroRNAs (miRNAs) are suggested to affect cellular behaviors including cell growth and apoptosis. This study concentrated on unraveling the emerging role...
Federico I Brigante et al.
Food chemistry, 312, 126059-126059 (2020-01-04)
Food fraud is perpetrated with increasing frequency along the food chain, triggering the need for new and modern tools to detect food authenticity. Chia, flax and sesame seeds are well known for the good nutritional characteristics of their oils, but...
Qi Li et al.
Molecular and cellular biochemistry, 466(1-2), 139-148 (2020-02-06)
Pirarubicin (THP), an anthracycline drug, is widely used as a basic therapeutic agent for the treatment of carcinoma and lymphatic malignant tumor. However, it exerts irreversible cardiotoxicity in varying degrees. At present, dexrazoxane (DZR) is the only cardioprotective agent used...
Natalia S Podio et al.
Chemosphere, 241, 125057-125057 (2019-10-20)
Pharmaceuticals in the environment have been an increasing research topic over the past decade, since they can be found in both natural and drinking water, including irrigation of crops and edible plants with contaminated water. Our main goal was to...
Sara Saeidikhoo et al.
Journal of molecular neuroscience : MN, 70(7), 1153-1163 (2020-03-14)
To date, no certain cure has been found for patients with degenerative cerebellar disease. In this trial, we examined the in vivo and in vitro neuroprotective effects of Sertoli cells (SCs) on alleviating the symptoms of cerebellar ataxia. Testicular cells...
Bo-Wen Wu et al.
IUBMB life, 72(2), 198-213 (2019-08-25)
Atherosclerotic plaque rupture is an important pathophysiologic mechanism of acute coronary syndrome. Emerging microRNAs (miRNAs) have been implicated in the atherosclerotic plaque formation and macrophage autophagy during the development of atherosclerosis (AS). Hence, this study was conducted to explore the...
Zupeng Chen et al.
Journal of integrative neuroscience, 19(1), 101-109 (2020-04-08)
Medicinal plant breviscapine is shown to exhibit a protective role in tissue damage after cerebral hemorrhage. The effects of breviscapine on neurological deficit score, brain tissue water content, brain pathological tissue changes, blood-brain barrier bidirectional regulation, and inflammatory factors after...