T84409

Triphenylphosphine

ReagentPlus^®, 99%

• Synonym(s): Phosphorustriphenyl
• Linear Formula: (C₆H₅)₃P
• CAS Number: 603-35-0
• Molecular Weight: 262.29
• Beilstein: 610776
• EC Number: 210-036-0
• MDL number: MFCD00003043
• PubChem Substance ID: 24900530

Properties

• vapor density: 9 (vs air)
• Quality Level: 200
• vapor pressure: 5 mmHg ( 20 °C)
• product line: ReagentPlus^®
• Assay: 99%
• reaction suitability: reaction type: Buchwald-Hartwig Cross Coupling Reaction; reaction type: Heck Reaction; reaction type: Hiyama Coupling; reaction type: Negishi Coupling; reaction type: Sonogashira Coupling; reaction type: Stille Coupling; reaction type: Suzuki-Miyaura Coupling; reagent type: ligand; reaction type: Cross Couplings
• bp: 377 °C (lit.)
• mp: 79-81 °C (lit.)
• functional group: phosphine
• SMILES string: c1ccc(cc1)P(c2ccccc2)c3ccccc3
• InChI: 1S/C18H15P/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15H
• InChI key: RIOQSEWOXXDEQQ-UHFFFAOYSA-N

Description

General description

Rhodium and triphenylphosphine catalyst system has been used for the hydroformylation of soybean, safflower and linseed oils and their methyl esters. Polymer supported triphenylphosphine has been reported to efficiently catalyze the γ-addition of pronucleophiles to alkynoate. Triphenylphosphine reacts with hydrated ruthenium trichloride in methanol to afford [RuCl₂(PPh₃)₄], [RuCl₂(PPh₃)₃] and [RuCl₃(PPh₃)₂CH₃OH]. It participates in the Heck reaction of 4-bromoanisole and ethyl acrylate in ionic liquids.

Application

Triphenylphosphine was used in the synthesis of mono-6-amino-deoxy-6-cyclodextrin. It was also employed as catalyst during the synthesis of C-aryl furanosides.

Legal Information

ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC

Safety Information

• Pictograms: GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H302 - H317 - H318 - H372
• Precautionary Statements: P260 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1B - STOT RE 1 Inhalation
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 2
• Flash Point(F): 356.0 °F - closed cup
• Flash Point(C): 180 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves