C3355

Coelenterazine hcp

solid

• Synonym(s): CLZN-hcp
• Empirical Formula (Hill Notation): C₂₅H₂₅N₃O₂
• CAS Number: 123437-32-1
• Molecular Weight: 399.48
• MDL number: MFCD03453204
• PubChem Substance ID: 24892609
• NACRES: NA.83

Properties

• Assay: ≥95% (HPLC)
• Quality Level: 200
• form: solid
• solubility: methanol: 1 mg/mL, clear, yellow to orange
• storage temp.: −20°C
• SMILES string: Oc1ccc(cc1)C2=CN3C(=O)C(Cc4ccccc4)=NC3=C(CC5CCCC5)N2
• InChI: 1S/C25H25N3O2/c29-20-12-10-19(11-13-20)23-16-28-24(21(26-23)14-17-8-4-5-9-17)27-22(25(28)30)15-18-6-2-1-3-7-18/h1-3,6-7,10-13,16-17,26,29H,4-5,8-9,14-15H2
• InChI key: YEGCUOQUFAXCMK-UHFFFAOYSA-N

Description

General description

Coelenterazine hcp is a semisynthetic analog of coelenterazine.

Application

Coelenterazine hcp has been used:

• as a component of coelenterazine reagent in the reporter assay
• in the purification of Renilla luciferase-labeled Annexin V
• in evaluating the activity of aequorin in Escherichia coli

Biochem/physiol Actions

Coelenterazine hcp has 190 times higher luminescence intensity than native coelenterazine and a faster response time than native coelenterazine.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315 - H319 - H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves