Merck
  • L1290
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L1290

Sigma-Aldrich

Lactoferricin B, fragment 4-14 trifluoroacetate salt

≥95% (HPLC)

Synonym(s):
bLFC (26-36), bovine lactoferricin
Empirical Formula (Hill Notation):
C70H113N25O13S
Molecular Weight:
1544.87
MDL number:
NACRES:
NA.32

Quality Level

Assay

≥95% (HPLC)

solubility

H2O: soluble

antibiotic activity spectrum

Gram-negative bacteria
Gram-positive bacteria

Mode of action

cell membrane | interferes

storage temp.

−20°C

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PH015918CDS013888CDS016074
assay

≥95% (HPLC)

assay

-

assay

-

assay

-

solubility

H2O: soluble

solubility

-

solubility

-

solubility

-

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

antibiotic activity spectrum

-

antibiotic activity spectrum

-

antibiotic activity spectrum

-

mode of action

cell membrane | interferes

mode of action

-

mode of action

-

mode of action

-

storage temp.

−20°C

storage temp.

-

storage temp.

-

storage temp.

-

Quality Level

200

Quality Level

-

Quality Level

-

Quality Level

-

Amino Acid Sequence

Arg-Arg-Trp-Gln-Trp-Arg-Met-Lys-Lys-Leu-Gly

General description

Chemical structure: peptide

Application

Lactoferricin B, fragment 4-14 trifluoroacetate salt has been used to study effect of lactoferricin on cell proliferation of human colon cancer cells. It has been used in study of ultraviolet light-mediated DNA damage in human colon cancer cells.

Biochem/physiol Actions

Lactoferricin B also suppresses liver and lung metastasis in murine melanomas and lymphomas. In addition, it causes cell death in human leukemic and carcinoma cell lines. It is effective against Escherichia coli, Salmonella enteritidis, Klebsiella pneumoniae, Proteus vulgaris, Yersinia enterocolitica, Pseudomonas aeruginosa, Campylobacter jejuni, Staphylococcus aureus, Streptococcus mutans, Corynebacterium diphtheriae, Listeria monocytogenes and Clostridium perfringens.
Antibiotic peptide in colostrum and milk that protects from bacterial infection at mucosal surfaces.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

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Certificate of Origin

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