L3908

β-Lactoglobulin from bovine milk

≥90% (PAGE), lyophilized powder

• Synonym(s): βLg, BLG, Bos d 5, beta-lactoglobulin
• CAS Number: 9045-23-2
• EC Number: 232-928-9
• MDL number: MFCD00130635
• NACRES: NA.61

Properties

• biological source: bovine milk
• Quality Level: 200
• Assay: ≥90% (PAGE)
• form: lyophilized powder
• technique(s): ELISA: suitable
• UniProt accession no.: P02754
• storage temp.: 2-8°C
• Gene Information: bovine ... LGB(280838)

Description

General description

Milk from dairy cows contains the protein β-lactoglobulin (BLG). It naturally occurs in a number of genetic variants, and the most prevalent bovine variants are BLG A and BLG B.

Application

β-Lactoglobulin was used in a cytologic assay for diagnosis of food hypersensitivity in patients with irritable bowel syndrome.

Biochem/physiol Actions

A member of the lipocalin family, βLg is a small protein of 162 amino acids with a molecular mass of ∼18,400 Da. It features an eight-stranded β-barrel (strands A-H) succeeded by a three-turn a-helix and a final β-strand (strand I) that forms part of the dimerization interface.

Other Notes

Contains β-lactoglobulins A and B which can be isolated chromatographically.

Quality

May not contain folate binding protein; not recommended for folate analysis.

Preparation Note

Chromatographically purified

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves