Merck
All Photos(5)

P6001

Sigma-Aldrich

p-Phenylenediamine

98% (GC)

Synonym(s):
1,4-Benzenediamine, 1,4-Diaminobenzene, 1,4-Phenylenediamine
Linear Formula:
C6H4(NH2)2
CAS Number:
Molecular Weight:
108.14
Beilstein:
742029
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.83

vapor density

3.7 (vs air)

Quality Level

vapor pressure

1.08 mmHg ( 100 °C)

description

anti-fade reagent

assay

98% (GC)

bp

267 °C (lit.)

mp

138-143 °C (lit.)

SMILES string

Nc1ccc(N)cc1

InChI

1S/C6H8N2/c7-5-1-2-6(8)4-3-5/h1-4H,7-8H2

InChI key

CBCKQZAAMUWICA-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

p-Phenylenediamine has been used:
  • to evaluate its sensitization potential in vitro in langerhans-like dendritic cells and autologous T cells[1]
  • to treat the dorsal sides of the ears of mice, to study its systemic immunological effects[2]
  • in glycerol to coverslip coronal sections in the attempt to count Aβ plaques[3]

Anti-fade reagent is added to the mounting medium in fluorescence microscopy to retard photobleaching of fluorescein and other fluorescent dyes.

Packaging

50, 100, 250 g in glass bottle
1 kg in glass bottle

Biochem/physiol Actions

p-Phenylenediamine causes allergic reactions with skin.[4] It is widely used in hair dyes. It eventually forms Bandrowski′s base, which is found to be the primary cause for allergy.[5] p-Phenylenediamine exposure results in dermatitis, urticaria and anaphylaxis.[6] It acts as an electron donor and is known to reduce cytochrome c.

Caution

Darkens in storage.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 1 Oral

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

230.0 °F - closed cup

Flash Point(C)

110 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificate of Analysis

Enter Lot Number to search for Certificate of Analysis (COA).

Certificate of Origin

Enter Lot Number to search for Certificate of Origin (COO).

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service