Lipids for Research
Lipids play diverse roles as fuel, energy stores, membrane components, and key players in signal transduction and metabolism. With their hydrophobic properties, lipids are vital for cellular function, exhibiting versatility and contributing to various physiological processes.
We offer a wide spectrum of lipids and their derivatives that can be grouped as below.
- Fatty acids, such as saturated, unsaturated & omega fatty acids
- Glycerides, including triglycerides and neutral glycerides
- Nonglyceride lipids, like steroids, fatty alcohols, terpenes, bacterial lipids, bile acids, bioactive lipids, fluorescent lipids, and natural lipids
- Complex lipids, including cardiolipins, sphingolipids, phospholipids, phosphoglycerides, cationic lipids, deuterated lipids, and lipid extracts
Along with the above categories, we also offer click reagents, stable isotopes, lipid extracts, and ESR probes to drive research and innovation across multiple applications. We are committed to empowering groundbreaking discoveries in drug delivery, transfection, lipidomics, and other lipid applications across your entire workflow. Our high-quality lipids can be used with high-performance liquid chromatography (HPLC), liquid chromatography-mass spectrometry (LC-MS), and nuclear magnetic resonance (NMR) spectroscopy.
With their diverse properties and functionalities, lipids play a pivotal role in shaping the landscape of scientific research and innovative therapies. Lipid research encompasses a broad range of areas and finds applications in various fields such as:
Lipidomics
Lipidomics employs techniques such as mass spectrometry, LC-MS, or NMR to comprehensively profile, identify, and quantify lipids and their metabolites. Such analysis is necessary to deepen our holistic understanding of the complex cellular mechanisms and lipid metabolic pathways contributing to lipid metabolism. The insights provided by lipidomics are essential for the mechanisms underpinning such conditions as obesity, diabetes, and cardiovascular diseases.
Lipids in Pharmacology & Immunology
Lipids play significant roles in drug development, delivery systems, and immunology. Advancements include lipid-based drug carriers, nanoparticles, and liposome formulations for targeted delivery, enhanced stability, and immune modulation. These applications underscore lipids' critical significance in research and therapeutic interventions.
Lipids in Cell Culture
Lipids play a vital role in cell culture by influencing cell membranes, signaling, and bioprocessing. Researchers analyze lipid composition and optimize supplementation to gain a broader understanding of lipid-mediated signaling, aiming to improve cell growth and achieve desired cellular functions. Such insights not only improve bioprocess efficiency but also hold implications for tissue engineering and regenerative medicine.
Lipids in Neurobiology and Biochemistry
Lipids play a vital role in neurobiology, brain development, neural signaling, and the study of lipid-related changes in neurodegenerative disorders. Furthermore, lipid research deepens our understanding of biochemical pathways, molecular mechanisms, lipid metabolism, protein interactions, signaling and cellular processes.
Lipids in Membrane Biology and Biophysics
Lipids are integral components of cell membranes. Research conducted in this area aims to elucidate the structure, dynamics, and functional properties of lipid bilayers. These fields of investigation delve into membrane biophysics, lipid-protein interactions, lipid-mediated signaling, and the role of lipids in membrane-related processes.
Related Product Resources
- Liposome Preparation - Avanti® Polar Lipids
Lipid vesicle preparation involves hydration and sizing steps, applicable regardless of lipid composition.
- Preparation of Cationic Liposomes & Transfection of Cells - Avanti® Polar Lipids
This procedure describes the Preparation of Cationic Liposomes & Transfection of Cells
- Procedure for Preparation of Cationic Lipid/Oligomer Complex - Avanti® Polar Lipids
This procedure describes the preparation of Cationic Lipid/Oligomer Complex.
- Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids
The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
- Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids
The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Dr. Anne Bendt - LipidMaps Podcast
This episode of the LipidMaps podcast features Dr. Anne Bendt, Deputy Director of the world-renowned Singapore Lipidomics Incubator (SLING). SLING specializes in mass spectrometry-based lipid analysis and, under Dr. Bendt's leadership, prioritizes practical applications and partnerships in academia and industry.
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