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The Progress in Development of Dental Restorative Materials
With dentists placing nearly 100 million dental fillings into patients′ teeth annually in the U.S. alone, polymeric composite restoratives account for a very large share of the biomaterials market.
Segmented Copolymers of p-dioxanone, Glycolide, and Lactide: Advantages and Applications in Biomedical
Main features of p-dioxanone, glycolide and lactide based copolymers
Functional Biomaterials Synthesized by Double-Head Polymerization Agents
Over the past two decades, the rapid advance of controlled living polymerization (CLP) techniques.
Smart Oligonucleotide Delivery by Multifunctional Block Copolymers
Kanjiro Miyata (The University of Tokyo, Japan) provides insights on the rational design of polymeric materials for “smart” oligonucleotide delivery.
Universal (Switchable) RAFT Agents for Well-Defined Block Copolymers
Universal (Switchable) RAFT agents allow for the polymerization of both less activated and more activated monomers and are ideal for the synthesis of well-defined block copolymers.
Functionalized PEI and Its Role in Gene Therapy
Gene therapy has become one of the most discussed techniques in biomedical research in recent years.
Introduction of Terminal Azide and Alkyne Functionalities in Polymers
Click chemistry, and the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) in particular, is a powerful new synthetic tool in polymer chemistry and material science.
Protein- and Peptide- Polymer Conjugates by RAFT Polymerization
The modification of biomacromolecules, such as peptides and proteins, through the attachment of synthetic polymers has led to a new family of highly advanced biomaterials with enhanced properties.
Functional RAFT Polymers for Biomedical Applications
Reversible addition–fragmentation chain transfer (RAFT) polymerization is rapidly moving to the forefront in construction of drug and gene delivery vehicles.
Block copolymer synthesis using a commercially available nitroxide-mediated radical polymerization (NMP) initiator
Block copolymer synthesis using a commercially available nitroxide-mediated radical polymerization (NMP) initiator
Polyethylene Glycol Building Blocks for PEGylation
Circulatory half-life is a key success factor for new drugs. In this respect, PEGylation or PEG-ing—the modification of potential candidates ranging from non-peptidic small molecules to peptides and proteins, antibody fragments, aptamers, and saccharides or oligonucleotides with polyethylene glycol chains—offers
Electrospinning: Enabling Nanostructured Materials
Electrospinning technique applications discussed, emphasizing control of nanofibers and assembly into 3D architectures.
Water-Soluble Photoinitiators
Water-dispersible photoinitiator nanoparticles enable novel formulations for 3D bioprinting, tissue engineering, and device manufacturing.
Fluorinated Hyperbranched Polymers
Fluorocarbon polymers exhibit increased thermal stability, hydrophobicity, lipophobicity, and chemical resistance compared to hydrocarbon analogs.
Materials for High and Low Refractive Index Coatings
Polymeric materials, with unique refractive index properties, find applications in photonics and optical coatings for various devices.
Initiator/Stabilizer FAQs
An article regarding common FAQs for initiators and stabilizers.
Polymer Analysis in Materials Science
Scientists at Sigma-Aldrich® routinely determine number-average molecular weight (Mn) by 1H NMR end-group analysis for polymers having Mn values under 3,000.
Versatile Cell Culture Scaffolds: Bio-orthogonal Click
Designing biomaterial scaffolds mimicking complex living tissue structures is crucial for tissue engineering and regenerative medicine advancements.
RAFT Agents for Functionalized Polymers
Low-cost, high-purity RAFT Agents are vital for industrial RAFT polymerization. We supply effective agents for this technology.
Synthesis of Polyamino Acids
Polyamino acids adopt ordered conformations with unique biological properties and functions like α-helices and β-sheets.
Molecular Layer Deposition of Polymers
Atomic layer deposition meets various needs including semiconductor device miniaturization and nanoparticle coating.
Asymmetric Polymerization in Chiral Liquid Crystals
Chiral nematic liquid crystal (N*-LC) facilitates asymmetric acetylene polymerization, yielding helical chains and fibrils in polyacetylene film.
High-Purity Monomers & Polymers for Ophthalmic Applications
We offer a continuously expanding selection of high-purity monomers and polymers for ophthalmic applications, along with a full range of initiators, crosslinkers, dyes, and solvents.
Nanoclays in Multi-Functional Composites
Nanoclays are clay minerals optimized for use in clay nanocomposites– multi-functional material systems with several property enhancements targeted for a particular application.
Hexafluoroalcohol-functionalized Methacrylate Monomers for Lithographic/nanopatterning materials
To keep pace with Moore′s Law, there is a continuing need in the semiconductor industry to achieve higher circuit density in microelectronic devices.
Innovative Materials for Glass Ionomer Cements (GICs): Dental Applications
Innovation in dental restorative materials is driven by the need for biocompatible and natural-appearing restoration alternatives. Conventional dental materials like amalgam and composite resins have inherent disadvantages.
RAFT: Choosing the Right Agent to Achieve Controlled Polymerization
Find reversible addition–fragmentation chain transfer(RAFT) polymerization process, classes of RAFT agents & applications.
Poly(N-isopropylacrylamide)-based Smart Surfaces for Cell Sheet Tissue Engineering
Tissue engineering has become a key therapeutic tool in the treatment of damaged or diseased organs and tissues, such as blood vessels and urinary bladders.
Designing Temperature and pH Sensitive NIPAM Based Polymers
Poly(N-isopropylacrylamide), or PNIPAM, is a stimuli-responsive polymer that responds to changes in pH and temperature and has a LCST around 32 C.
Chemistry at Surfaces with Self-Assembled Monolayers and SAMDI-ToF Mass Spectrometry
Chemistry at Surfaces with Self-Assembled Monolayers and SAMDI-ToF Mass Spectrometry
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