261556

（L）-脱氢抗坏血酸

• Synonym(s): DHAA, Dehydro-L-ascorbate, Dehydro-L-ascorbic acid, oxidized ascorbic acid, oxidized vitamin C
• Empirical Formula (Hill Notation): C₆H₆O₆
• CAS Number: 490-83-5
• Molecular Weight: 174.11
• EC 号: 207-720-6
• MDL编号: MFCD00066467
• PubChem化学物质编号: 24855820
• NACRES: NA.22

Properties

• 形式: powder
• 质量水平: 200
• mp: 228 °C (dec.) (lit.)
• 储存温度: −20°C
• SMILES string: OC[C@H](O)[C@H]1OC(=O)C(=O)C1=O
• InChI: 1S/C6H6O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-8H,1H2/t2-,5+/m0/s1
• InChI key: SBJKKFFYIZUCET-JLAZNSOCSA-N

Description

一般描述

(L)-Dehydroascorbic acid (DHA) is a potent glycation agent that is produced by the oxidation of ascorbic acid (vitamin C). In vitro studies revealed that DHA is significantly more reactive than glucose and fructose in the glycation of lens proteins. Thus, DHA could be a critical precursor for the in vivo formation of advanced glycation end products (AGEs).
DHA is a dimer when it is solid, but when it is dissolved in a solution, it becomes a monomer.

应用

(L)-Dehydroascorbic acid can be used as a starting material to synthesize:

• Pyrano[3,4-b]indole derivatives by reacting with 2-hydroxymethylindole.
• (−)-ascorbyl phloroglucinol via stereoselective C-C bond formation reaction with phloroglucinol.

包装

250 mg in glass bottle

1, 5 g in glass bottle

Safety Information

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 3
• 闪点(F): Not applicable
• 闪点(C): Not applicable
• 个人防护装备: dust mask type N95 (US), Eyeshields, Gloves