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Merck

39391

Sigma-Aldrich

1-(3-二甲基氨基丙基)-3-乙基碳二亚胺

≥97.0% (T), for peptide synthesis

别名:

N-乙基-N′-(3-二甲基氨丙基)碳二亚胺, EDC, WSC

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10 ML
$434.00
50 ML
$1,290.00

$434.00


预计发货时间2025年5月13日详情


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10 ML
$434.00
50 ML
$1,290.00

About This Item

经验公式(希尔记法):
C8H17N3
CAS号:
分子量:
155.24
Beilstein:
507429
EC號碼:
MDL號碼:
分類程式碼代碼:
12352116
PubChem物質ID:
NACRES:
NA.22

$434.00


预计发货时间2025年5月13日详情


Request a Bulk Order

产品名称

1-(3-二甲基氨基丙基)-3-乙基碳二亚胺, ≥97.0% (T)

品質等級

化驗

≥97.0% (T)

形狀

liquid

反應適用性

reaction type: Coupling Reactions

折射率

n20/D 1.461

密度

0.877 g/mL at 20 °C (lit.)

應用

peptide synthesis

官能基

amine

儲存溫度

−20°C

SMILES 字串

CCN=C=NCCCN(C)C

InChI

1S/C8H17N3/c1-4-9-8-10-6-5-7-11(2)3/h4-7H2,1-3H3

InChI 密鑰

LMDZBCPBFSXMTL-UHFFFAOYSA-N

一般說明

N-(3-二甲基氨基丙基)-N′-乙基羰基二胺和 N-羟基丁二酰亚胺(NHS)经常一起使用,在碳二亚胺偶联反应中激活羰基基团,和胺偶联形成酰胺。[1]

應用

N-(3-二甲基氨基丙基)-N′-乙基羰基二胺可用于石墨烯量子点(GQDs)表面官能化,作为传感器探针,在Janus微电机上探测肠道菌感染。[2]它还可以在和硅纳米颗粒交联前,激活叶酸。[3]

訊號詞

Danger

危險分類

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A - Skin Sens. 1A - STOT RE 2 Oral

標靶器官

Stomach,large intestine,lymph node

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Questions

1–4 of 4 Questions  
  1. Which is the suggested EDC concentration and the relative protocol for covalently attach haptens to carrier proteins (e.g. BSA) ?

    1 answer
    1. EDC and EDAC are both abbreviations for N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide. While a detailed procedure for conjugating haptens (such as peptides) to carrier proteins such as Bovine Serum Albumin (BSA) is not available, the EDC is typically used at a 5 to 10-fold molar excess with respect to the hapten concentration in the reaction mix. Note that EDC hydrochloride (e.g., Products E6383, E7750 and 03450) is more commonly used as a coupling agent than EDC free base (Product 39391).

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  4. What is the concentration of the EDC chemical in the 10mL solution?

    1 answer
    1. This product is considered to be a pure/neat EDC material. It has a purity specification of 97% or greater, but it is not a solution of EDC in a solvent.

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