Merck
All Photos(1)

438227

Sigma-Aldrich

羟胺 溶液

50 wt. % in H2O

Synonym(s):
HDA
Linear Formula:
NH2OH
CAS Number:
Molecular Weight:
33.03
EC 号:
MDL编号:
PubChem化学物质编号:

蒸汽压

9 mmHg ( 40 °C)

质量水平

200

形式

liquid

浓度

50 wt. % in H2O

bp

>100 °C

密度

1.078 g/mL at 25 °C

SMILES string

NO

InChI

1S/H3NO/c1-2/h2H,1H2

InChI key

AVXURJPOCDRRFD-UHFFFAOYSA-N

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一般描述

羟胺是一种弱碱,主要用作有机反应中的还原剂。

应用

作为制备下列化合物的反应物:
  • 心血管药物 Nω-羟基-L-精氨酸(NOHA,一氧化氮前体)的前药
  • 羟基氨基胍,作为抗癌药
  • 非甾体2,3-二氢喹啉糖皮质激素受体激动剂,具有降低的磷酸烯醇丙酮酸羧基激酶(PEPCK)转录激活活性
  • 氧氟沙星的羧酰胺衍生物,具有改善的抗菌特性
  • 基于香豆素类似物的TNF-α转化酶(TACE)抑制剂
  • HIV整合酶抑制剂

包装

50, 250 mL in poly bottle

警示用语:

Danger

危险分类

Acute Tox. 4 Oral - Aquatic Acute 1 - Carc. 2 - Desen. Expl. 4 - Eye Dam. 1 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 - STOT SE 3

靶器官

Blood, Respiratory system

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificate of Analysis

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Certificate of Origin

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