492876

L-Alanine-¹²C₃

99.9 atom % ¹²C

• 线性分子式: ¹²CH3¹²CH(NH2)¹²CO2H
• CAS号: 56-41-7
• 分子量: 89.06
• Beilstein: 1720248
• EC 号: 200-273-8
• MDL编号: MFCD00198168
• PubChem化学物质编号: 24872786

属性

• 描述: ¹³C-depleted
• 同位素纯度: 99.9 atom % ¹²C
• 旋光性: [α]25/D +14.5°, c = 2 in 1 M HCl
• availability: available only in Japan
• mp: 314.5 °C (dec.) (lit.)
• 质量偏移: depleted
• SMILES string: [12CH3][12C@H](N)[12C](O)=O
• InChI: 1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1/i1+0,2+0,3+0
• InChI key: QNAYBMKLOCPYGJ-BWIFZRRMSA-N

说明

生化/生理作用

L-Alanine is a nonessential amino acid, which is highly concentrated in muscle. It is a key player in the Glucose-Alanine cycle, which enables the removal of pyruvate and glutamate from muscle to the liver. Once in the liver, glucose is regenerated from pyruvate and returned to the muscle while glutamate ultimately participates in the urea cycle to form urea. The Glucose-Alanine cycle aides to conserve ATP in muscle for muscle contraction, while the energy burden of gluconeogenesis is imposed upon the liver. Alanine inhibits pyruvate kinase to regulate gluconeogenesis and glycolysis in order to maintain glucose homeostasis during starvation. Alanine prevents hepatic autophagy. Alanine formation is a result of transamination of glutamate and pyruvate.

包装

This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.

安全信息

• 储存分类代码: 13 - Non Combustible Solids
• WGK: WGK 1
• 闪点(F): Not applicable
• 闪点(C): Not applicable