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品質等級
化驗
98%
折射率
n20/D 1.559 (lit.)
bp
250 °C (lit.)
mp
2-5 °C (lit.)
密度
1.065 g/mL at 25 °C (lit.)
SMILES 字串
CCOc1ccc(N)cc1
InChI
1S/C8H11NO/c1-2-10-8-5-3-7(9)4-6-8/h3-6H,2,9H2,1H3
InChI 密鑰
IMPPGHMHELILKG-UHFFFAOYSA-N
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訊號詞
Warning
危險分類
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Muta. 2 - Skin Sens. 1
水污染物質分類(WGK)
WGK 1
個人防護裝備
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Chemical research in toxicology, 4(4), 489-496 (1991-07-01)
4-Ethoxyaniline (p-phenetidine) is oxidized by peroxidases to form several products, one of which is 4-[(4-ethoxyphenyl)imino]-2,5-cyclohexadien-1-one (1). This compound reacts with N-acetylcysteine (NAC) in methanol-phosphate buffers, generating at least four different products. Four major products, 4-[(4-ethoxyphenyl)amino]phenol (2), 3-(N-acetylcystein-S-yl)-4-[(4-ethoxyphenyl)amino]phenol (3), 2,5-bis(N-acetylcystein-S-yl)-4-[(4-ethoxyphenyl)-amino]phenol (4)
Postgraduate medical journal, 83(978), 251-260 (2007-04-04)
Targeted biologic therapies have revolutionised treatment of immune-mediated inflammatory diseases (IMIDs) due to their efficacy, speed of onset and tolerability. The discovery that clinically unrelated conditions, such as rheumatoid arthritis and Crohn's disease, share similar immune dysregulation has led to
The Journal of pharmacology and experimental therapeutics, 235(2), 475-480 (1985-11-01)
The metabolism of p-phenetidine in microsomes from rabbit kidney and the metabolism of acetaminophen and p-phenetidine in human kidney microsomes to protein binding metabolites were examined. Microsomal preparations from rabbit kidney medulla catalyzed the irreversible arachidonic acid-dependent binding of p-[14C]phenetidine
Chemico-biological interactions, 60(3), 317-330 (1986-12-01)
The interaction of N-(4-ethoxyphenyl)p-benzoquinone imine (NEPBQI), a metabolite formed during peroxidase catalyzed metabolism of p-phenetidine, with GSH and its effects in isolated rat hepatocytes were investigated. When reacted with GSH NEPBQI formed both a mono- and a diglutathione conjugate as
Journal of chromatography, 353, 329-337 (1986-02-26)
Liquid chromatographic methods were developed for the study of the in vitro acetylation of the sulphonamide drug sulphamethazine and a series of aniline derivatives. The sensitivity of the methods have allowed data on the activity of the N-acetyltransferase enzyme(s) in
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