Merck
All Photos(1)

1.01736

Sigma-Aldrich

OSTEOMOLL®

Solution for rapid decalcification (with fixation) for histology

质量水平

400

形式

liquid

颜色

blue

pH值(酸碱度)

<1 (20 °C in H2O)

密度

1.10 g/mL at 20 °C

application(s)

diagnostic assay manufacturing
hematology
histology

储存温度

15-25°C

一般描述

OSTEOMOLL® - Solution for rapid decalcification (with fixation) for histology, is used for human cell diagnostics and serves to decalcify (demineralize) bone tissue (e. g. punched bone-marrow specimens) and other hard materials and to soften keratinized tissue of human origin, fixing the specimens in the same process.
Decalcification is necessary for optical microscopic examinations of hard tissue in routine histological procedures. For the decalcification of sensitive, calcium-containing tissues, such as iliac crest biopsies, OSTEOSOFT® (Product number 1.01728) can be used. Its formulation is based on EDTA. Its pendant, OSTEOMOLL®, can be used for the decalcification of hard tissue such as teeth and bone as its formulation is based on formaldehyde and hydrochloric acid. The amount of OSTEOMOLL® needed is dependent upon on the size, type and thickness of the material. A 30 ml portion of OSTEOMOLL®, which should completely cover the material, can be used twice if the solution is still clear and not contaminated.
The material must first be cut to a thickness of max. 5 mm and an area of 6 cm2 (= max. Embedding cassette size). Both solutions are color-coded, to distinguish them from each other, fixatives and solvents used in the histological laboratory. OSTEOSOFT® is color-coded yellow, OSTEOMOLL® is color-coded blue. Whereby OSTEOSOFT® preserves the antigen structures in the tissue, thus, an IHC analysis can be performed, OSTEOMOLL® will be used for tissues that are not destined for antibody analysis.
Both decalcifiers can be used for clinical diagnostic purposes and in laboratory accreditation processes as they are certified and registered as IVD and CE product. The quantity of OSTEOMOLL® required is dependent on the size, type, and density of the respective material. For more details, please see instructions for use (IFU). The IFU can be downloaded from this webpage.

包装

1, 2.5 l in Plastic bottle

分析说明

Performance test: passes test

法律信息

OSTEOMOLL is a registered trademark of Merck KGaA, Darmstadt, Germany
OSTEOSOFT is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语:

Danger

危险分类

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Met. Corr. 1 - Muta. 2 - Skin Corr. 1 - Skin Sens. 1 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

Certificate of Analysis

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Certificate of Quality

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