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  • 341006
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341006

Sigma-Aldrich

EDAC，盐酸盐

EDAC HCl is a water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis.

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Synonym(s):
EDAC，盐酸盐, EDCI，1-乙基-3-(3 ʹ-二甲基氨基丙基)碳二亚胺，HCl
Empirical Formula (Hill Notation):
C8H17N3 · xHCl
CAS Number:
25952-53-8
Molecular Weight:
155.24 (free base basis)
MDL编号:
MFCD00012503

质量水平

200

测定

≥98% (titration)

形式

solid

manufacturer/tradename

Calbiochem®

储存条件

OK to freeze
desiccated

颜色

white

溶解性

aqueous buffer: 2-5 mg/mL
water: 2-5 mg/mL

运输

ambient

储存温度

−20°C

InChI

1S/C8H17N3.ClH/c1-4-11(8-9)7-5-6-10(2)3;/h4-7H2,1-3H3;1H

InChI key

FDXPUDRRFDHONO-UHFFFAOYSA-N

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03449E6383E7750
EDAC, Hydrochloride EDAC HCl is a water-soluble derivative of carbodiimide useful for conjugating haptens to proteins and polypeptides. Used to modify NMDA receptors and as a condensing agent in peptide synthesis.

Sigma-Aldrich

341006

EDAC，盐酸盐

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride ≥99.0% (AT)

Sigma-Aldrich

03449

N-（3-二甲基氨基丙基）-N'-乙基碳二亚胺 盐酸盐

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride crystalline

Sigma-Aldrich

E6383

N-（3-二甲基氨基丙基）-N'-乙基碳二亚胺 盐酸盐

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride commercial grade, powder

Sigma-Aldrich

E7750

N-（3-二甲基氨基丙基）-N'-乙基碳二亚胺 盐酸盐

assay

≥98% (titration)

assay

≥99.0% (AT)

assay

-

assay

-

form

solid

form

powder

form

crystalline

form

powder

color

white

color

-

color

-

color

-

solubility

aqueous buffer: 2-5 mg/mL, water: 2-5 mg/mL

solubility

H2O: soluble 0.2 g/L

solubility

H2O: ≤100 mg/mL

solubility

H2O: ≤100 mg/mL

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

300

一般描述

摩尔吸光系数（~212 nm；50 mM磷酸盐缓冲液，pH 8）：≥6800 M-1cm-1。
水溶性碳二亚胺衍生物。用于修饰NMDA受体。还可以用于将半抗原与蛋白质或多肽结合。
碳二亚胺的水溶性衍生物，可用于将半抗原与蛋白质和多肽结合。用于修饰NMDA受体，并在肽合成中用作缩合剂。EDAC偶联的主要优势在于可通过用稀酸或水洗涤而轻松去除过量的试剂和相应的尿素。碳二亚胺可通过活化羧酸酯以形成O-酰脲来催化酰胺键、羧酸和胺的形成。该中间体可被胺直接攻击以形成酰胺。EDAC作为可溶性尿素衍生物而被释放。

包装

用惰性气体包装

警告

毒性：刺激性（B）

制备说明

避免使用含有胺的缓冲液。

重悬

溶液中不稳定。仅在使用前进行重悬。

其他说明

Chazot, P.L., et al. 1993.生物化学。Pharmacol.45, 605.
Richardson, A., et al. 1992.生物化学。Pharmacol.43, 1415.
Taniuchi, M., et al. 1986.《美国Natl.Acad.Sci. USA83, 1950.
Chase, J.W., et al. 1983.Proc.Natl.Acad.Sci. USA80, 5480.
Williams, A., et al. 1981.J. Am. Chem. Soc.103, 7090.
Yamada, H., et al. 1981.Biochemistry20, 4836.
Thomas, J.O., et al. 1978.J. Mol.Biol.123, 149.
Ozawa, H. 1970.Biochemistry9, 2158.
Kopple, K.D., et al. 1962.J. Am. Chem. Soc.84, 4457.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

警示用语：

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(F)

Not applicable

闪点(C)

Not applicable

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