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Sigma-Aldrich

N-(3-二甲基氨基丙基)-N′-乙基碳二亚胺盐酸盐

for peptide synthesis

别名:

N-(3-二甲基氨基丙基)-N′-乙基碳二亚胺盐酸盐

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500 MG
$51.70

$51.70


预计发货时间2025年5月26日详情


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选择尺寸

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500 MG
$51.70

About This Item

经验公式(希尔记法):
C8H17N3 · xHCl
CAS号:
分子量:
155.24 (free base basis)
MDL编号:
UNSPSC代码:
12352107
EC索引号:
247-361-2
NACRES:
NA.22

$51.70


预计发货时间2025年5月26日详情


Request a Bulk Order

产品名称

N-(3-二甲基氨基丙基)-N′-乙基碳二亚胺盐酸盐, for synthesis

质量水平

表单

solid

反应适用性

reaction type: Coupling Reactions

mp

110-115 °C

应用

peptide synthesis

储存温度

−20°C (−15°C to −25°C)

SMILES字符串

Cl.N(CCCN(CC)C#N)(C)C

InChI

1S/C8H17N3.ClH/c1-4-11(8-9)7-5-6-10(2)3;/h4-7H2,1-3H3;1H

InChI key

FDXPUDRRFDHONO-UHFFFAOYSA-N

一般描述

N-(3-二甲基氨基丙基)-N-乙基碳二亚胺盐酸盐也称EDAC HCl或WSC,是一种水溶性缩合剂。EDAC HCl常用于羧酸和胺偶联生成酰胺。副产物尿素是水溶性的,可以通过水萃取从不混溶的反应环境中除去。它主要用于溶液相肽合成和作为零长度交联剂修饰蛋白质。

应用

N-(3-二甲基氨基丙基)-N′-乙基碳二亚胺盐酸盐(EDC盐酸盐)可被用作:
  • 水溶性碳二亚胺,可促进醇中的肽偶联反应。[1]
  • 偶联剂,与 HOBt 一起合成聚(谷氨酸)(PGA)多肽,用于制备可用于各种生物医学应用的防污多肽。[2]
  • 偶联剂,用于工业规模的高效合成特立氟胺。[3]

警示用语:

Danger

危险分类

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 2 Oral

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. The packaging instructions recommend storing the item under an inert gas, but the safety data sheet does not specify this requirement. Would it suffice to store it in a refrigerator at -20°C instead?

    1 answer
    1. The recommended long term storage of this item is -15°C to -25°C. Clearing the headspace of the vial with argon before resealing is recommended. The stability of the product when stored otherwise cannot be guaranteed.

      Helpful?

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