8.52037

Fmoc-Asp-OtBu

Novabiochem^®

• 别名: Fmoc-Asp-OtBu, N-α-Fmoc-L-aspartic acid α-t.-butyl ester
• Empirical Formula (Hill Notation): C₂₃H₂₅NO₆
• CAS号: 129460-09-9
• 分子量: 411.45

属性

• 质量水平: 200
• 产品线: Novabiochem^®
• 检测方案: ≥90.0% (acidimetric); ≥98% (TLC); ≥98.0% (HPLC)
• 形式: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 90-98 °C
• application(s): peptide synthesis
• 官能团: carboxylic acid
• 储存温度: 2-30°C
• InChI: 1S/C23H25NO6/c1-23(2,3)30-21(27)19(12-20(25)26)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,25,26)/t19-/m0/s1
• InChI key: VZXQYACYLGRQJU-IBGZPJMESA-N

说明

一般描述

Selectively protected building block for library synthesis or the preparation of β-aspartyl peptides by Fmoc SPPS. After condensation of the side-chain carboxy with an appropriate amine or alcohol, the β-amino and carboxy functions can be selectively unmasked with 20% piperidine in DMF and 50% TFA in DCM respectively, facilitating the synthesis of branched esters and amides, and lactams and lactones containing the aspartyl unit.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

联系

Replaces: 04-12-1080

分析说明

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.0 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 90.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

安全信息

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 2
• 闪点(F): Not applicable
• 闪点(C): Not applicable