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文件

COA分析证书/COQ

8.55001

Rink Amide resin (100-200 mesh)

Novabiochem^®

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别名:

4-(2′,4′-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxy resin

Show Differences

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此商品	8.55061	8.55004	8.55003
Sigma-Aldrich 8.55001 Rink Amide resin (100-200 mesh)	Sigma-Aldrich 8.55061 HMPB-MBHA resin	Sigma-Aldrich 8.55004 Rink Amide AM树脂（200-400目）	Sigma-Aldrich 8.55003 Rink Amide MBHA树脂（100-200目）
form beads	form beads	form beads	form beads
reaction suitability reaction type: Fmoc solid-phase peptide synthesis	reaction suitability reaction type: Fmoc solid-phase peptide synthesis	reaction suitability reaction type: Fmoc solid-phase peptide synthesis	reaction suitability reaction type: Fmoc solid-phase peptide synthesis
application(s) peptide synthesis	application(s) peptide synthesis	application(s) peptide synthesis	application(s) peptide synthesis
functional group amine	functional group alcohol	functional group amine	functional group amine
storage temp. 2-30°C	storage temp. 2-30°C	storage temp. 2-30°C	storage temp. 2-30°C

一般描述

An excellent support for the Fmoc SPPS of peptide amides. This resin is more acid-sensitive than Rink Amide AM and Rink Amide MBHA resins. Cleavage with high concentrations of TFA can lead to the breakdown of the linker, with the concomitant formation of by-products that can not be removed by simple washes. These problems appear to be minimized through the use of low TFA concentrations or by the addition of trialkyl silanes to the cleavage mixture.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

联系

Replaces: 01-64-0013

分析说明

Color (visual): white to pale yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
TNBS-Test: passes test
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH₂Cl₂): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.2 ml/g
The polymer matrix is copoly (styrene-1 % DVB) 100 - 200 mesh.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

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25G

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1000309185

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商品

Linkers for Fmoc SPPS

Novabiochem® has one of the most extensive ranges of linkers and derivatized resins for Fmoc solid phase peptide synthesis. These resins have varied properties with special protocols for loading and cleaving.

实验方案

Peptide Resin Loading Protocols

Review methods and resins for attaching amino acids and peptides, including Merrifield, trityl-based, and hydroxymethyl-functionalized resins. Resin-immobilized peptides can be used for various downstream applications.

文件

Rink Amide resin (100-200 mesh)

Novabiochem^®

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