8.55008

Sieber Amide resin

Novabiochem^®

• Synonym(s): Sieber Amide resin, 9-Fmoc-amino-xanthen-3-yloxy-Merrifield resin
• CAS Number: 915706-90-0

Properties

• 质量水平: 400
• 产品线: Novabiochem^®
• 形式: beads
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• 官能团: amine
• 储存温度: 2-8°C

Description

一般描述

A hyper acid-labile linker for the Fmoc SPPS of protected peptide amides via mild 1% TFA cleavage [1, 2]. The resin can be readily reductively alkylated to provide a support suited to the synthesis of secondary carboxamides [3].

This resin has also been employed to produce protected peptide fragments in which the C-terminal carboxylic acid group is blocked as a hydroxymethylphenoxy-β-alaninamide ester [4].

The product number for this product was previously 01-64-0059.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

联系

Replaces: 01-64-0059

分析说明

Color (visual): white to light yellow to beige
Appearance of substance (visual): beads
Loading (Photometric determination of the Fmoc-chromophore liberated upon treatment with DBU/DMF): 0.40 - 0.80 mmol/g
Swelling Volume (in DMF): lot specific result
Swelling Volume (in CH₂Cl₂): lot specific result
Total swelling volume acc. Houben Weyl (in CH₂Cl₂): ≥ 5.2 ml/g
Total swelling volume acc. Houben Weyl (in DMF): ≥ 5.2 ml/g
The polymer matrix is copoly (styrene - 1% DVB) 100 -200 mesh

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• 储存分类代码: 11 - Combustible Solids
• WGK: WGK 1
• 闪点(F): Not applicable
• 闪点(C): Not applicable