Merck
All Photos(1)

8.55016

Sigma-Aldrich

Rink Amide PEGA resin

Novabiochem®

All Photos(1)

质量水平

200

产品线

Novabiochem®
PEGA

形式

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

manufacturer/tradename

Novabiochem®

application(s)

peptide synthesis

官能团

amine

储存温度

2-8°C

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This Item
8.550018.55004
Rink Amide PEGA resin Novabiochem®

Sigma-Aldrich

8.55016

Rink Amide PEGA resin

Rink Amide resin (100-200 mesh) Novabiochem®

Sigma-Aldrich

8.55001

Rink Amide resin (100-200 mesh)

Rink Amide AM resin (200-400 mesh) Novabiochem®

Sigma-Aldrich

8.55004

Rink Amide AM树脂（200-400目）

product line

Novabiochem®, PEGA

product line

Novabiochem®

product line

Novabiochem®

form

beads

form

beads

form

beads

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

application(s)

peptide synthesis

functional group

amine

functional group

amine

functional group

amine

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

2-30°C

一般描述

An excellent acid-labile support for the solid phase synthesis of peptide amides. This resin is prepared by derivatization of amino PEGA resin with the modified Rink linker. It is supplied without Fmoc protection of the linker benzhydrylamine group as this has been found to improve stability. Cleavage is effected with 95% TFA.PEGA-based resins are compatible with aqueous and alcoholic solvents, and are permeable to macromolecules up to 35 kD. For further information, please refer to the product entry for amino PEGA resin (855015).Note: PEGA resins are supplied swollen in ethanol, with 1g dry resin corresponding to approximately 15 mL of swollen resin. As the beads of PEGA resins become very sticky and easily damaged when shrunk or dried, they are best handled in a swollen state. To use, the appropriate amount of swollen resin should be weighed into a reaction vessel and any residual ethanol removed by copious washings with the appropriate solvent or solvent mixture. After peptide assembly, the resin should be washed with DCM and transferred to the cleavage vessel. Excess DCM can be removed under vacuum, and the shrunk resin treated with the TFA cocktail. The characteristics of the swollen resin, its robustness and high permeability enables its use in both batch and continuous flow synthesis apparatus.

Associated Protocols and Technical Articles
Protocols for Loading of Peptide Synthesis Resins

联系

Replaces: 01-64-0101

分析说明

Color (visual): white to yellow to beige
Appearance of substance (visual): beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin): 0.20 - 0.50 mmol/g
Swelling Volume (in DMF): lot specific result
dry resin %: lot specific result
The resin is sold swollen ethanol.

法律信息

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

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