Merck
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文件

15527

Sigma-Aldrich

甘氨酸

meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

所有图片(1)
别名:
氨基乙酸, 甘氨酸
线性分子式:
NH2CH2COOH
CAS号:
56-40-6
分子量:
75.07
Beilstein:
635782
EC 号:
200-272-2
MDL编号:
MFCD00008131
eCl@ss:
32160406
PubChem化学物质编号:
57647473
NACRES:
NA.21

质量水平

200

检测方案

99-101% (based on anhydrous substance)

形式

crystalline powder

质量

meets analytical specification of Ph. Eur., BP, USP

technique(s)

IR spectroscopy: suitable

杂质

hydrolyzable substances, complies
 organic volatile impurities, complies (GC)
 residual solvents, complies
≤0.001% heavy metals (as Pb)
≤1.0% ninhydrin-positive substances

灼烧残渣

≤0.1% (as SO4)

缺失

≤0.2% loss on drying, 105 °C, 2 h

颜色

white

pH值（酸碱度）

5.9-6.4 (20 °C, 5%)

pKa (25 °C)

(1) 2.35, (2) 9.60
2.35

mp

240 °C (dec.) (lit.)

溶解性

H2O: soluble 25 gm in 100 ml at 25 degrees c
H2O: soluble 39.1 gm in 100 ml at 50 degrees c
alcohol: soluble 0.06 gm in 100 gm (Absolute)
pyridine: soluble 164 parts
alcohol: very slightly soluble
diethyl ether: very slightly soluble

痕量阴离子

chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤50 mg/kg

适用性

complies for appearance of solution
complies for reaction against H2SO4
in accordance for identity (IR)

SMILES string

NCC(O)=O

InChI

1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChI key

DHMQDGOQFOQNFH-UHFFFAOYSA-N

Gene Information

rat ... Grin2a(24409)

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此商品
41022533226G7403
Glycine meets analytical specification of Ph. Eur., BP, USP, 99-101% (based on anhydrous substance)

Sigma-Aldrich

15527

甘氨酸

Glycine ACS reagent, ≥98.5%

Sigma-Aldrich

410225

甘氨酸

Glycine puriss. p.a., reag. Ph. Eur., buffer substance, 99.7-101% (calc. to the dried substance)

Sigma-Aldrich

33226

甘氨酸

Glycine BioXtra, ≥99% (titration)

Sigma-Aldrich

G7403

甘氨酸

form

crystalline powder

form

crystals, powder or granules

form

crystalline powder

form

powder

technique(s)

IR spectroscopy: suitable

technique(s)

-

technique(s)

IR spectroscopy: suitable

technique(s)

electron microscopy: suitable

impurities

hydrolyzable substances, complies, organic volatile impurities, complies (GC), residual solvents, complies, ≤0.001% heavy metals (as Pb), ≤1.0% ninhydrin-positive substances

impurities

H2SO4, passes test (darkened), Hydrolyzable subsances, passes test

impurities

≤0.001% heavy metals (as Pb), ≤0.02% ammonium (NH4), ≤0.1% water (Karl Fischer), ≤1.0% ninhydrin-positive substances

impurities

Insoluble matter, passes filter test

color

white

color

-

color

-

color

white

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

mp

240 °C (dec.) (lit.)

应用

使用甘氨酸制备全血样本中的血小板，并研究白细胞中细胞因子表达的刺激。用于生化和耐受性试验。

生化/生理作用

甘氨酸通过激活中枢神经系统，在降低糖尿病和肥胖患者的血脂水平中发挥关键作用。脑缺氧时，甘氨酸能稳定脑线粒体的能量紊乱。当与葡萄糖一起使用时，它也增加了猪囊胚的体外发育。
脊髓中的抑制性神经递质，NMDA受体的变构调节器。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(F)

Not applicable

闪点(C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Slide 1 of 5

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Glycine suitable for electrophoresis, ≥99%

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甘氨酸

Glycine analytical standard, for nitrogen determination according to Kjeldahl method

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Glycine GR for analysis

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甘氨酸

Glycine Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR1111

甘氨酸

Glycine ACS reagent, ≥98.5%

Sigma-Aldrich

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甘氨酸

A A Selin et al.
Bulletin of experimental biology and medicine, 153(1), 44-47 (2012-07-19)
Glycine stabilizes energetics of brain mitochondria under conditions of brain hypoxia in vivo modeled by ligation of the common carotid artery in rats. Hypoxia reduced respiratory control in brain cortex mitochondria from 7.7 ± 0.5 to 4.5 ± 0.3. Preliminary
Tomomi Mito et al.
Reproduction, fertility, and development, 24(3), 443-450 (2012-03-10)
In the present study, the effects of glucose and/or glycine on the in vitro development of Day 5 (Day 0=IVF) porcine blastocysts were determined. The addition of 2.5-10 mM glucose to the chemically defined culture medium porcine zygote medium (PZM)-5
F J Neumann et al.
Circulation, 95(10), 2387-2394 (1997-05-20)
Activated platelets tether and activate myeloid leukocytes. To investigate the potential relevance of this mechanism in acute myocardial infarction (AMI), we examined cytokine induction by leukocyte-platelet adhesion and the occurrence of leukocyte-platelet conjugates in patients with AMI. We obtained peripheral
Jessica T Y Yue et al.
Circulation research, 110(10), 1345-1354 (2012-04-05)
Dysregulation of hepatic triglyceride (TG)-rich very low-density lipoproteins (VLDL-TG) in obesity and type 2 diabetes contributes to the dyslipidemia that leads to cardiovascular morbidity. The central nervous system (CNS), particularly the hypothalamus, regulates hepatic lipid metabolism. Although the underlying neurocircuitry
F Megraud et al.
Journal of clinical microbiology, 22(6), 1007-1010 (1985-12-01)
"Campylobacter pyloridis" has been recently described as a gastritis-associated bacterium. We studied 20 strains. The bacteria had most of the characteristics of Campylobacter spp. strains. They were hippurate negative and tolerant to triphenyl tetrazolium chloride (at 0.4 and 1 mg/ml).
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