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Merck

69479

Supelco

N-甲基-N-(三甲基硅烷基)三氟乙酰胺

N-Methyl-N-(trimethylsilyl)trifluoroacetamide

derivatization grade (GC derivatization), LiChropur, ≥98.5%

别名:

N-三甲基硅基-N-甲基三氟乙酰胺, MSTFA

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5 ML
$282.00
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$454.00
25 ML
$858.00

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5 ML
$282.00
10 X 1 ML
$454.00
25 ML
$858.00

About This Item

线性分子式:
CF3CON(CH3)Si(CH3)3
CAS号:
分子量:
199.25
Beilstein:
1941550
EC 号:
MDL编号:
UNSPSC代码:
23151817
PubChem化学物质编号:
NACRES:
NA.22

$282.00


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等级

derivatization grade (GC derivatization)

质量水平

蒸汽密度

>1 (vs air)

蒸汽压

8.8 mmHg ( 27 °C)

方案

≥98.5% (GC)
≥98.5%

表单

liquid

质量

LiChropur

反应适用性

reagent type: derivatization reagent
reaction type: Silylations

技术

gas chromatography (GC): suitable

折射率

n20/D 1.38 (lit.)
n20/D 1.380

沸点

130-132 °C (lit.)

密度

1.075 g/mL at 25 °C (lit.)

储存温度

2-8°C

SMILES字符串

CN(C(=O)C(F)(F)F)[Si](C)(C)C

InChI

1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3

InChI key

MSPCIZMDDUQPGJ-UHFFFAOYSA-N

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一般描述

N-甲基-N-(三甲基甲硅烷基)三氟乙酰胺(MSTFA)是一种甲硅烷基化试剂。[1]

应用

更多信息请参见产品信息
MSTFA可用于甲硅烷基化过程,以使用GC-MS对类固醇激素17α-乙炔雌二醇(EE2)和雌酮进行测定。MSTFA与三甲基甲硅烷基氯(TMCS)一起在乙酸乙酯、乙腈和二氯甲烷溶剂中可导致三甲基甲硅烷基(TMS)和丁基二甲基甲硅烷基(TBS)衍生物的形成。[1]
适用于胺,氨基酸,羧基,羟胺,吲哚烷基胺,正亚硝基氨基酸,核苷,酚烷基胺,5-羟色胺和色胺的衍生化。

其他说明

用于N-乙酰基-N,三氟乙酰基,三甲基甲硅烷基,N-三甲基甲硅烷基-N-三氟乙酰基和O-三甲基甲硅烷基(TMS)的试剂
高效硅烷化试剂[2][3][4][5]

法律信息

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

象形图

FlameExclamation mark

警示用语:

Warning

危险分类

Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

3 - Flammable liquids

WGK

WGK 3

闪点(°F)

77.0 °F - closed cup

闪点(°C)

25 °C - closed cup

个人防护装备

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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J. Heberle et al.
Silylating Agents, 2nd ed. (1995)
Hieng-Ming Ting et al.
Frontiers in plant science, 11, 257-257 (2020-03-27)
Glucosinolates are defense-related secondary metabolites found in Brassicaceae. When Brassicaceae come under attack, glucosinolates are hydrolyzed into different forms of glucosinolate hydrolysis products (GHPs). Among the GHPs, isothiocyanates are the most comprehensively characterized defensive compounds, whereas the functional study of
Journal of Chromatography A, 115, 591-591 (1975)
M. Donike
Chromatographia, 9, 440-440 (1976)
Chanhee Jo et al.
Experimental & molecular medicine, 52(12), 2005-2019 (2020-12-15)
Acetylation is the most studied histone acyl modification and has been recognized as a fundamental player in metabolic gene regulation, whereas other short-chain acyl modifications have only been recently identified, and little is known about their dynamics or molecular functions

商品

Development and validation of a fatty acid methyl esterification method, using methanolic HCl reagent, for FAME analysis by GC of vegetable oils and fats.

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

实验方案

Example displays how MSTFA/MSTFA-d9 derivatization of amphetamine provides valuable information in mass spectra and chromatograms using SLB-5ms GC column.

示例显示了使用SLB-5ms GC色谱柱的苯丙胺的MSTFA/MSTFA-d9衍生化如何在质谱图和色谱图中提供有价值的信息。

相关内容

Results of a study involving the ability few Fluka silylating reagents to form GC-MS-compatible trimethylsilylmethyl derivatives of NSAIDs

Questions

1–3 of 3 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  3. What is the packaging of the product N-Methyl-N-(trimethylsilyl)trifluoroacetamide, code: 69479-10X1ML, bottle, ampoule, blister or other??

    1 answer
    1. The 1ML size is packaged in a 5mL amber glass vial with a Schwarz-type septum cap. The vials are then placed in a 10-place overpack box with dividers to protect each vial. Please see the image below of this cap type.

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