87472

氯化氢 - 1-丁醇 溶液

~3 M in 1-butanol, for GC derivatization, LiChropur^™

• CAS Number: 7647-01-0
• Beilstein: 1098214
• MDL编号: MFCD00011324
• PubChem化学物质编号: 329769583
• NACRES: NA.22

Properties

• 等级: for GC derivatization
• 质量水平: 100
• 形式: solution
• 质量: LiChropur^™
• reaction suitability: reagent type: derivatization reagent; reaction type: Acylations
• 浓度: ~3 M in 1-butanol
• technique(s): gas chromatography (GC): suitable
• 密度: 0.87 g/mL at 20 °C
• 储存温度: 2-8°C
• SMILES string: Cl
• InChI: 1S/ClH/h1H
• InChI key: VEXZGXHMUGYJMC-UHFFFAOYSA-N

Description

一般描述

Acylation, an alternative to silylation, is the conversion of compounds that contain active hydrogens (-OH, -SH and -NH) into esters, thioesters, and amides through the action of a carboxylic acid or derivative. The presence of a carbonyl group adjacent to the halogenated carbons enhances electron capture detector (ECD) response. Acylation has many benefits:

• It improves the stability of compounds by protecting unstable groups.
• It may confer volatility on substances such as carbohydrates or amino acids, which have so many polar groups that they are non-volatile and normally decompose on heating.
• It assists in separations not possible with underivatized compounds.
• Compounds are detectable at very low levels with an ECD.

Hydrogen chloride-1-butanol is a reagent utilized to form fragmentation-directing derivatives for GC/MS analysis.

应用

Hydrogen chloride - 1-butanol solution has been used for butylation of amino acids during blood sample analysis for determination of ethylenediaminetetraacetic acid using mass spectrometry.

其他说明

GC-MS 分析氨基酸和肉碱的酯化试剂[1]

法律信息

LiChropur is a trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• 象形图: GHS02,GHS05,GHS07
• 警示用语：: Danger
• 危险声明: H226 - H290 - H302 - H315 - H318 - H335 - H336
• 预防措施声明: P210 - P233 - P280 - P301 + P312 - P303 + P361 + P353 - P305 + P351 + P338
• 危险分类: Acute Tox. 4 Oral - Eye Dam. 1 - Flam. Liq. 3 - Met. Corr. 1 - Skin Irrit. 2
• 储存分类代码: 3 - Flammable liquids
• WGK: WGK 1
• 个人防护装备: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter